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氟碳等离子体对纳米结构表面的杀菌性能

Bactericidal performance of nanostructured surfaces by fluorocarbon plasma.

作者信息

Vassallo E, Pedroni M, Silvetti T, Morandi S, Toffolatti S, Angella G, Brasca M

机构信息

CNR, Institute of Plasma Physics, Via R. Cozzi 53, 20125 Milan, Italy.

CNR, Institute of Plasma Physics, Via R. Cozzi 53, 20125 Milan, Italy.

出版信息

Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:117-121. doi: 10.1016/j.msec.2017.05.111. Epub 2017 May 19.

Abstract

This study presents the characterization and antibacterial activity of nanostructured Si by plasma treatment method using a tetrafluoromethane (CF) and hydrogen (H) mixture. Nanostructured-Si is a synthetic nanomaterial that contains high aspect ratio nanoprotrusions on its surface, produced through a reactive-ion etching process. We have shown that the nanoprotrusions on the surfaces produce a mechanical bactericidal effect. Nanostructured-Si exhibited notable activity against three different microorganisms: Gram-negative (Escherichia coli), Gram-positive (Staphylococcus aureus) and spore-forming bacteria (Bacillus cereus) producing a > 5 log reduction after 24h of incubation. Scanning electron microscopy was used to analysis the structure and morphology character of different surfaces evidencing the physical bactericidal activity of the Nanostructured-Si. These results provide excellent prospects for the development of a new generation of antibacterial surfaces.

摘要

本研究介绍了采用四氟甲烷(CF)和氢气(H)混合气体通过等离子体处理方法制备的纳米结构硅的特性及其抗菌活性。纳米结构硅是一种合成纳米材料,其表面含有高纵横比的纳米突起,通过反应离子蚀刻工艺制备而成。我们已经表明,表面的纳米突起产生机械杀菌作用。纳米结构硅对三种不同的微生物表现出显著活性:革兰氏阴性菌(大肠杆菌)、革兰氏阳性菌(金黄色葡萄球菌)和产芽孢细菌(蜡样芽孢杆菌),孵育24小时后细菌数量减少超过5个对数级。使用扫描电子显微镜分析不同表面的结构和形态特征,证明了纳米结构硅的物理杀菌活性。这些结果为新一代抗菌表面的开发提供了极好的前景。

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