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用于食品工业的机械杀菌纳米拓扑结构:一种消除食源性病原体的有前景策略——进展与挑战

Mechanobactericidal nanotopographies for food industry: A promising strategy for eradicating foodborne pathogens - progress and challenges.

作者信息

Patil Deepak

机构信息

Department of Production Engineering, National Institute of Technology Tiruchirappalli, 620015, India.

出版信息

J Food Drug Anal. 2024 Dec 15;32(4):385-397. doi: 10.38212/2224-6614.3532.

DOI:10.38212/2224-6614.3532
PMID:39752862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11698595/
Abstract

Nowadays, food preservation, quality maintenance, and safety are major emerging concerns in the food industry. Methods for removing pathogens from the outside surfaces of food products would be an effective way to prevent bacterial contamination. Nanotopographies found on natural surfaces have been shown to mechanically damage the membranes of foodborne bacteria. Thus, using bioinspired mechanobactericidal nanostructures in food packaging and processing materials has the potential to lower surface bacterial contamination while increasing food safety. However, putting this concept into practice remains a challenge. This review discussed recent advances in understanding mechanobactericidal mechanisms, issues concerning the durability of nanotopography under external forces, and the scalability of nanostructures over larger areas. Furthermore, this review provides insight into critical research on the long-term efficiency of mechanobactericidal nanostructures and their potential for implementation in the food industry.

摘要

如今,食品保鲜、质量维持和安全是食品工业中主要出现的问题。从食品产品外表面去除病原体的方法将是预防细菌污染的有效途径。已表明天然表面上发现的纳米拓扑结构会机械损伤食源细菌的细胞膜。因此,在食品包装和加工材料中使用受生物启发的机械杀菌纳米结构有可能降低表面细菌污染,同时提高食品安全。然而,将这一概念付诸实践仍然是一项挑战。本综述讨论了在理解机械杀菌机制方面的最新进展、关于纳米拓扑结构在外力作用下的耐久性问题以及纳米结构在更大面积上的可扩展性。此外,本综述深入探讨了关于机械杀菌纳米结构的长期效率及其在食品工业中实施潜力的关键研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/e00a69fb162a/jfda-32-04-385f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/036bc74733ef/jfda-32-04-385f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/67b019c2360b/jfda-32-04-385f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/222cc9da0d5e/jfda-32-04-385f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/f62c244c0b3a/jfda-32-04-385f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/e00a69fb162a/jfda-32-04-385f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/036bc74733ef/jfda-32-04-385f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/67b019c2360b/jfda-32-04-385f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/222cc9da0d5e/jfda-32-04-385f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/f62c244c0b3a/jfda-32-04-385f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6c7/11698595/e00a69fb162a/jfda-32-04-385f5.jpg

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本文引用的文献

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Cooperative stiffening of flexible high aspect ratio nanostructures impart mechanobactericidal activity to soft substrates.柔性高纵横比纳米结构的协同硬化赋予软质基底机械杀菌活性。
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Bioinspired nanotopography on 3D printed tissue scaffold to impart mechanobactericidal and osteogenic activities.三维打印组织支架上的仿生纳米形貌赋予抗菌和成骨活性。
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Mechanobactericidal Nanotopography on Nitrile Surfaces toward Antimicrobial Protective Gear.
在腈纶表面构建具有杀菌作用的纳米形貌结构以制备抗菌防护装备。
ACS Macro Lett. 2023 Feb 21;12(2):227-233. doi: 10.1021/acsmacrolett.2c00697. Epub 2023 Jan 27.
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Multi-directional electrodeposited gold nanospikes for antibacterial surface applications.用于抗菌表面应用的多向电沉积金纳米尖刺
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Nano-engineering safer-by-design nanoparticle based moth-eye mimetic bactericidal and cytocompatible polymer surfaces.基于纳米工程设计更安全的仿蛾眼纳米颗粒的杀菌且细胞相容的聚合物表面。
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Bactericidal effect of nanostructures lytic transglycosylases of .纳米结构溶菌转糖基酶的杀菌作用 。 (原文表述不太完整规范,翻译出来的句子也稍显奇怪,推测可能是“Bactericidal effect of nanostructures and lytic transglycosylases of...”这样更完整的表述 )
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