Qian Hongchang, Li Minglu, Li Zhong, Lou Yuntian, Huang Luyao, Zhang Dawei, Xu Dake, Du Cuiwei, Lu Lin, Gao Jin
Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing 100083, China.
Department of Chemical and Biomolecular Engineering, Institute for Corrosion and Multiphase Technology, Ohio University, Athens, OH 45701, USA.
Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:566-577. doi: 10.1016/j.msec.2017.07.002. Epub 2017 Jul 5.
In this study, a multilayer antibacterial film was assembled onto 316L stainless steel via mussel-inspired depositions of polydopamine (PDA) and silver (Ag) nanoparticles followed by post-modification with 1H, 1H, 2H, 2H-perfluorodecanethiol. The resulting surface exhibited excellent superhydrophobicity with hierarchical micro/nanostructures that were constructed by both PDA and Ag nanoparticles. The crystal structure and chemical composition of these surfaces were investigated using X-ray photoelectron spectroscopy (XPS) analysis. Potentiodynamic polarization measurements revealed that the corrosion resistance of the as-prepared surfaces were sequentially increased after each step of the fabrication process. Compared with the surface covered with only Ag nanoparticles, the superhydrophobic surfaces exhibited substantially enhanced antibacterial activity against the Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, resulting from the synergistic antibacterial actions of the superhydrophobic surface and Ag nanoparticles. The superhydrophobic surface exhibited lower cytotoxicity, compared to the surface covered with Ag nanoparticles.
在本研究中，通过受贻贝启发的聚多巴胺（PDA）和银（Ag）纳米颗粒沉积，然后用1H，1H，2H，2H-全氟癸硫醇进行后修饰，将多层抗菌膜组装到316L不锈钢上。所得表面呈现出优异的超疏水性，具有由PDA和Ag纳米颗粒构建的分级微/纳米结构。使用X射线光电子能谱（XPS）分析研究了这些表面的晶体结构和化学成分。动电位极化测量表明，在制造过程的每个步骤之后，所制备表面的耐腐蚀性依次增加。与仅覆盖有Ag纳米颗粒的表面相比，超疏水表面对革兰氏阴性大肠杆菌和革兰氏阳性金黄色葡萄球菌表现出显著增强的抗菌活性，这是由超疏水表面和Ag纳米颗粒的协同抗菌作用所致。与覆盖有Ag纳米颗粒的表面相比，超疏水表面表现出较低的细胞毒性。
