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使用 24 小时尿碘排泄测量维多利亚时代学童的碘摄入量。

Iodine Intakes of Victorian Schoolchildren Measured Using 24-h Urinary Iodine Excretion.

机构信息

Institute for Physical Activity and Nutrition, Deakin University, Locked Bag 20000, Waurn Ponds, Geelong, VIC 3220, Australia.

Department of Human Nutrition, University of Otago, 362 Leith St, North Dunedin, Dunedin 9016, New Zealand.

出版信息

Nutrients. 2017 Aug 30;9(9):961. doi: 10.3390/nu9090961.

Abstract

Mandatory fortification of bread with iodized salt was introduced in Australia in 2009, and studies using spot urine collections conducted post fortification indicate that Australian schoolchildren are now replete. However an accurate estimate of daily iodine intake utilizing 24-h urinary iodine excretion (UIE μg/day) has not been reported and compared to the estimated average requirement (EAR). This study aimed to assess daily total iodine intake and status of a sample of primary schoolchildren using 24-h urine samples. Victorian primary school children provided 24-h urine samples between 2011 and 2013, from which urinary iodine concentration (UIC, μg/L) and total iodine excretion (UIE, μg/day) as an estimate of intake was determined. Valid 24-h urine samples were provided by 650 children, mean (SD) age 9.3 (1.8) years ( = 359 boys). The mean UIE of 4-8 and 9-13 year olds was 94 (48) and 111 (57) μg/24-h, respectively, with 29% and 26% having a UIE below the age-specific EAR. The median (IQR) UIC was 124 (83,172) μg/L, with 36% of participants having a UIC < 100 μg/L. This convenience sample of Victorian schoolchildren were found to be iodine replete, based on UIC and estimated iodine intakes derived from 24-h urine collections, confirming the findings of the Australian Health Survey.

摘要

强制性在面包中添加碘化盐的做法于 2009 年在澳大利亚推出,而对强化后进行的随机尿液采集研究表明,澳大利亚学童现在的碘摄入量已很充足。但是,利用 24 小时尿液碘排泄量(UIEμg/天)来准确估计每日碘摄入量并与估计平均需求量(EAR)进行比较的报告尚未见诸于文献。本研究旨在利用 24 小时尿液样本评估小学生的日常总碘摄入量和碘营养状况。维州的小学生在 2011 年至 2013 年间提供了 24 小时尿液样本,从中测定了尿碘浓度(UIC,μg/L)和总碘排泄量(UIE,μg/天),以估计摄入量。650 名儿童提供了有效的 24 小时尿液样本,平均(标准差)年龄为 9.3(1.8)岁(=359 名男孩)。4-8 岁和 9-13 岁儿童的平均 UIE 分别为 94(48)和 111(57)μg/24 小时,分别有 29%和 26%的儿童 UIE 低于年龄特异性 EAR。UIC 的中位数(IQR)为 124(83,172)μg/L,有 36%的参与者 UIC<100μg/L。根据 UIC 和 24 小时尿液收集推断的碘摄入量,本维州随机抽样的学童被发现碘营养充足,这与澳大利亚健康调查的结果一致。

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