细菌微管蛋白：一种类似真核生物的微管细胞骨架。

Bacterial Tubulins: A Eukaryotic-Like Microtubule Cytoskeleton.

机构信息

Institut Curie, PSL Research University, CNRS UMR3348, F-91405 Orsay, France; INSERM, U1196, Université Paris Sud, Université Paris-Saclay, F-91405 Orsay, France.

Institut Pasteur, Unité de Microbiologie Structurale, CNRS UMR3528 & Université Paris Diderot, 25 rue du Dr Roux, 75724 Paris, France.

出版信息

Trends Microbiol. 2017 Oct;25(10):782-784. doi: 10.1016/j.tim.2017.08.004. Epub 2017 Aug 28.

DOI:10.1016/j.tim.2017.08.004

PMID:28869086

Abstract

Ever since their discovery, bacterial tubulins, found in several Prosthecobacter species, have raised curiosity as they are closely related to eukaryotic tubulin. Deng and colleagues now present new evidence for the functional homology of the two cytoskeletal systems where in vitro reconstituted Btub-microtubules display eukaryote-like biochemical and dynamic properties.

摘要

自从在几种 Prosthecobacter 物种中发现细菌微管蛋白以来，由于它们与真核微管蛋白密切相关，因此引起了人们的好奇心。邓及其同事现在提供了两个细胞骨架系统功能同源性的新证据，体外重建的 Btub-微管显示出类似真核生物的生化和动态特性。