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体外膜肺氧合(ECMO)支持且镇静困难患者混合性谵妄的早期诊断与处理:一例报告

The early diagnosis and management of mixed delirium in a patient placed on ECMO and with difficult sedation: A case report.

作者信息

Acevedo-Nuevo María, González-Gil Maria Teresa, Romera-Ortega Miguel Ángel, Latorre-Marco Ignacio, Rodríguez-Huerta Maria Dolores

机构信息

Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain; Universidad Autónoma de Madrid, Madrid, Spain.

Universidad Autónoma de Madrid, Madrid, Spain.

出版信息

Intensive Crit Care Nurs. 2018 Feb;44:110-114. doi: 10.1016/j.iccn.2017.07.013. Epub 2017 Aug 30.

DOI:10.1016/j.iccn.2017.07.013
PMID:28869145
Abstract

Delirium represents a serious problem that impacts the physical and cognitive prognosis of patients admitted to intensive care units and requires prompt diagnosis and management. This article describes the case and progress of a patient placed on Extracorporeal Membrane Oxygenation with difficult sedation criteria and an early diagnosis of mixed delirium. During the case report, we reflect on the pharmacological and non-pharmacological strategies employed to cope with delirium paying special attention to the non-use of physical restraint measures in order to preserve vital support devices (endotracheal tube or Extracorporeal Membrane Oxygenation cannula). The multimodal and multidisciplinary approach, focused on nursing interventions, strict Pain/Agitation/Delirium monitoring and pharmacological measures, as well as the implementation of measures according to the eCASH (early Comfort using Analgesia, minimal Sedatives and maximal Human Care) concept, were effective, resulting in a relatively short admission considering the severity of the patient's condition and the associated complications. Early independent ambulation was achieved prior to transfer to a hospitalisation unit.

摘要

谵妄是一个严重问题,影响入住重症监护病房患者的身体和认知预后,需要及时诊断和处理。本文描述了一名接受体外膜肺氧合治疗、镇静标准困难且早期诊断为混合性谵妄患者的病例及治疗过程。在病例报告中,我们思考了用于应对谵妄的药物和非药物策略,特别关注不使用身体约束措施以保护重要支持设备(气管插管或体外膜肺氧合插管)。以护理干预、严格的疼痛/躁动/谵妄监测和药物措施为重点的多模式、多学科方法,以及根据eCASH(早期舒适使用镇痛、最小化镇静和最大化人文关怀)理念实施的措施是有效的,考虑到患者病情的严重程度和相关并发症,住院时间相对较短。在转至住院病房之前实现了早期独立行走。

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J Thorac Dis. 2020 May;12(5):2179-2187. doi: 10.21037/jtd.2020.04.38.
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Dement Geriatr Cogn Dis Extra. 2019 Dec 5;9(3):374-380. doi: 10.1159/000502685. eCollection 2019 Sep-Dec.