[不同估算肾小球滤过率水平下肱踝脉搏波速度与动脉硬化的相关性]
[The correlation of brachial ankle pulse wave velocity with arterosclerosis at different estimated levels of glomerular filtration rate].
作者信息
Yu J X, Zhao Q H, Li W, Li J J, Wang M, Ning C H, Zhang Y J, Wu S L
机构信息
Department of Cardiology, Kailuan General Hospital, Tangshan 063000, China.
出版信息
Zhonghua Nei Ke Za Zhi. 2017 Sep 1;56(9):673-676. doi: 10.3760/cma.j.issn.0578-1426.2017.09.010.
To explore the relationship between brachial ankle artery pulse wave velocity of the (baPWV) in different estimation GFR (eGFR) groups and atherosclerosis.In 2010, 2012 and 2014, eGFR and baPWV were detected in 1 427 healthy persons.As eGFR level decreased, baPWV increased accordingly with higher proportion of baPWV ≥1 400 cm/s.The percentage of eGFR lower than 60 ml·min·1.73 m was similar in subgroups with different baPWV.However, the proportion of eGFR reduction≥30% decreased according to the elevation of baPWV.Multivariate logistic regression analysis indicated the lower the eGFR, the higher the risk of atherosclerosis.Low eGFR is an independent risk factor for atherosclerosis.
探讨不同估算肾小球滤过率（eGFR）分组的肱踝动脉脉搏波速度（baPWV）与动脉粥样硬化之间的关系。在2010年、2012年和2014年，对1427名健康人检测了eGFR和baPWV。随着eGFR水平降低，baPWV相应升高，baPWV≥1400 cm/s的比例更高。不同baPWV亚组中eGFR低于60 ml·min·1.73 m²的百分比相似。然而，随着baPWV升高，eGFR降低≥30%的比例下降。多因素逻辑回归分析表明，eGFR越低，动脉粥样硬化风险越高。低eGFR是动脉粥样硬化的独立危险因素。
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