School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada.
Li Ka Shing Knowledge Institute of St. Michael's Hospital, Department of Pediatrics and Nutritional Sciences, Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Prostaglandins Leukot Essent Fatty Acids. 2017 Sep;124:11-16. doi: 10.1016/j.plefa.2017.08.003. Epub 2017 Aug 14.
Omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) are important in child development. The primary objective of this study was to investigate the associations between dietary intakes of n-3 LCPUFA and red blood cell (RBC) n-3 LCPUFA in young children. Healthy children, (2-8y) underwent RBC fatty acid profiling. Dietary intakes were parent-reported over 6 mo using three 24h dietary intake assessments and three 30 d food frequency questionnaires (FFQ). Participants (n = 49, 5.6 ± 1.9y), were 59% male, and had a body mass index (BMI) z-score of 0.65 ± 0.84. Dietary n-3 LCPUFA intakes were not different over time. RBC docosahexaenoic acid (DHA) positively correlated with average DHA from the 24h recalls. RBC DHA and eicosapentaenoic acid (EPA) positively correlated with average n-3 LCPUFA-rich fish intake from the FFQ. RBC appear to reflect long-term stable intakes of n-3 LCPUFA during growth in healthy young children.
ω-3 长链多不饱和脂肪酸（n-3 LCPUFA）在儿童发育中很重要。本研究的主要目的是调查 n-3 LCPUFA 的饮食摄入量与幼儿红细胞（RBC）n-3 LCPUFA 之间的关联。健康的儿童（2-8 岁）接受了 RBC 脂肪酸分析。通过 3 次 24 小时饮食摄入评估和 3 次 30 天食物频率问卷（FFQ），家长在 6 个月内报告了饮食摄入量。参与者（n=49，5.6±1.9 岁）中 59%为男性，体重指数（BMI）z 分数为 0.65±0.84。饮食 n-3 LCPUFA 摄入量在不同时间没有差异。RBC 二十二碳六烯酸（DHA）与 24 小时回忆中的平均 DHA 呈正相关。RBC DHA 和二十碳五烯酸（EPA）与 FFQ 中平均富含 n-3 LCPUFA 的鱼类摄入量呈正相关。RBC 似乎反映了健康幼儿生长过程中 n-3 LCPUFA 的长期稳定摄入。
