Paniccia Melissa, Paniccia David, Thomas Scott, Taha Tim, Reed Nick
Rehabilitation Sciences Institute, University of Toronto, 500 University Avenue, Toronto, Ontario M5G 1V7, Canada; Concussion Research Centre, Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Road, Toronto, Ontario M4G 7A2, Canada.
Faculty of Kinesiology and Physical Education, University of Toronto, 55 Harbord Street, Toronto, Ontario M5S 2W6, Canada.
Auton Neurosci. 2017 Dec;208:1-14. doi: 10.1016/j.autneu.2017.08.008. Epub 2017 Aug 26.
Heart rate variability (HRV), a measure of cardiac autonomic nervous system functioning, has emerged as a physiological indicator for emotional regulation and psychological well-being. HRV is understudied in the context of depression and anxiety in young people (10-24years old). Main objectives: (1) describe the nature and breadth of reviewed studies; and (2) synthesize main findings in the context of clinical and non-clinical populations of young people with depression and/or anxiety.
The Arksey and O'Malley methodology was utilized for this scoping review. CINHAL, EMBASE, Medline, PsychInfo, Scopus, Web of Science, as well as grey literature, were searched. Two reviewers screened titles, abstracts and full papers for inclusion. A total of 20 citations were included in the final review (19 citations peer-reviewed journal articles, 1 journal abstract). Numerical and thematic analysis was used to summarize study findings.
In clinical populations of either depression or anxiety, HRV was lower compared to controls. In non-clinical populations of either depression or anxiety, HRV was found to be lower in those who reported more depression or anxiety symptoms.
The quality of the reviewed articles was not assessed which limits the ability to generate conclusions regarding study findings.
Changes in HRV were found across the spectrum of clinical and non-clinical populations of young people with depression or anxiety. Neurophysiological research on depression and anxiety in young people can act as a first step to understanding how physiological flexibility (i.e. HRV) is related to psychological flexibility (i.e. adaptive or maladaptive responses to life events).
心率变异性（HRV）是衡量心脏自主神经系统功能的指标，已成为情绪调节和心理健康的生理指标。在年轻人（10 - 24岁）的抑郁和焦虑背景下，HRV的研究较少。主要目标：（1）描述综述研究的性质和范围；（2）在患有抑郁和/或焦虑的临床和非临床年轻人群体背景下综合主要研究结果。
本综述采用了阿克西和奥马利的方法。检索了CINHAL、EMBASE、Medline、PsychInfo、Scopus、科学网以及灰色文献。两名评审员筛选标题、摘要和全文以确定是否纳入。最终综述共纳入20篇文献（19篇同行评审期刊文章，1篇期刊摘要）。采用数值和主题分析来总结研究结果。
在抑郁或焦虑的临床人群中，HRV低于对照组。在抑郁或焦虑的非临床人群中，报告有更多抑郁或焦虑症状的人HRV较低。
未评估所综述文章的质量，这限制了就研究结果得出结论的能力。
在患有抑郁或焦虑的临床和非临床年轻人群体中均发现了HRV的变化。关于年轻人抑郁和焦虑的神经生理学研究可作为理解生理灵活性（即HRV）与心理灵活性（即对生活事件的适应性或适应不良反应）之间关系的第一步。
