a Internal Medicine, Endocrinologist. Centro de Investigación en Matemáticas (CIMAT) , Nuevo Leon , Mexico.
c Internal Medicine, Endocrinologist, Instituto de Seguridad y Servicio Sociales de los trabajadores del Estado de Nuevo León (ISSSTELEON) , Nuevo Leon , Mexico.
Psychol Health Med. 2018 Mar;23(3):325-336. doi: 10.1080/13548506.2017.1363897. Epub 2017 Sep 5.
Depression and anxiety are hightly prevalent among patients with Type 2 Diabetes (T2D), however not commonly related to outcomes, treatment and comorbidities. Eating behaviors could also have an implication. To evaluate the relation between mood and eating behaviors with demographic, physical, treatment, biochemical profiles and chronic comorbidities in T2D we conducted this exploratory cross sectional study in a population from Mexico. Hospital Anxiety and Depression Scale and the Three Factor Eating Questionnaire Revised 21 (TFEQ-R21) were correlated with age, gender, blood pressure, treatment and comorbidities (nephropathy, neuropathy, retinopathy and cardiopathy). Multi-linear regression models and 2 factorial analyses were conducted. Sixty-one patients (31 male) 55 years old (SD 13) with at least 5 years of T2D were included. Anxiety correlated with depression (r = 0.25, p < 0.05). Gender (women) (std B 0.026, p < 0.001), insulin therapy (std B 0.3, p = 0.11), systolic blood pressure (std B 0.263, p = 0.02) and cardiovascular disease (std B 0.232, p = 0.035) predicted depression. Insulin therapy had a positive effect in cognitive restraint. (std B 0.32, p = 0.001). Age (std B 0.37, p = 0.003) and systolic blood pressure (std B 0.237, p = 0.048) predicted positively emotional eating (not previously published). 2 factorial analyses proved additive interaction between complications and insulin therapy with depression. This study supports the relation between mood disorders and eating behaviors with demographic, physical, treatment, biochemical profiles and chronic comorbidities in T2D and the additive interaction between factors and mood disorders.
抑郁和焦虑在 2 型糖尿病（T2D）患者中非常普遍，但与结局、治疗和合并症通常没有关系。饮食行为也可能有影响。为了评估 T2D 患者的情绪和饮食行为与人口统计学、身体、治疗、生化特征和慢性合并症之间的关系，我们在墨西哥的一个人群中进行了这项探索性横断面研究。医院焦虑和抑郁量表和三因素饮食问卷修订版 21（TFEQ-R21）与年龄、性别、血压、治疗和合并症（肾病、神经病、视网膜病变和心脏病）相关。进行了多元线性回归模型和 2 因子分析。纳入了 61 名患者（31 名男性），年龄 55 岁（标准差 13 岁），患有 T2D 至少 5 年。焦虑与抑郁相关（r=0.25，p<0.05）。性别（女性）（标准 B 0.026，p<0.001）、胰岛素治疗（标准 B 0.3，p=0.11）、收缩压（标准 B 0.263，p=0.02）和心血管疾病（标准 B 0.232，p=0.035）预测抑郁。胰岛素治疗对认知抑制有积极影响。（标准 B 0.32，p=0.001）。年龄（标准 B 0.37，p=0.003）和收缩压（标准 B 0.237，p=0.048）正性预测情绪性进食（未发表）。2 因子分析证明了并发症和胰岛素治疗与抑郁之间的附加交互作用。这项研究支持 T2D 患者的情绪障碍和饮食行为与人口统计学、身体、治疗、生化特征和慢性合并症之间的关系，以及这些因素与情绪障碍之间的附加交互作用。
