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当蛙视网膜视杆细胞被氧化时,观察到瞬态敏感性降低和双相光反应。

Transient sensitivity reduction and biphasic photoresponses observed when frog retinal rods are oxidized.

作者信息

Donner K, Hemilä S, Koskelainen A

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;87(3):749-56. doi: 10.1016/0300-9629(87)90394-x.

Abstract
  1. Rod photoresponses and the effects of oxidation have been studied by recording either the transretinal voltage in aspartate-treated retinas or the outer segment current of single rods. 2. Oxidizing conditions transiently decreased, reducing conditions increased sensitivity. 3. Biphasic photoresponses were seen when the level of oxidation was rising and also in some other sensitivity-depressing conditions. 4. A model is proposed which explains the biphasic responses in terms of sensitivity differences between the tip and the base of the rod outer segment.
摘要
  1. 通过记录天冬氨酸处理的视网膜中的跨视网膜电压或单个视杆的外段电流,对视杆光反应及氧化作用进行了研究。2. 氧化条件下反应短暂降低,还原条件下敏感性增加。3. 当氧化水平上升时以及在其他一些降低敏感性的条件下,可见双相光反应。4. 提出了一个模型,该模型根据视杆外段尖端和基部之间的敏感性差异来解释双相反应。

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