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外科医生改良开窗/分支覆膜支架移植物治疗有症状的复杂性主动脉病变或局限性破裂的疗效

Outcome of Surgeon-Modified Fenestrated/Branched Stent-Grafts for Symptomatic Complex Aortic Pathologies or Contained Rupture.

作者信息

Tsilimparis Nikolaos, Heidemann Franziska, Rohlffs Fiona, Diener Holger, Wipper Sabine, Debus E Sebastian, Kölbel Tilo

机构信息

1 German Aortic Center Hamburg, Department of Vascular Medicine, University Heart Center of Hamburg, Germany.

出版信息

J Endovasc Ther. 2017 Dec;24(6):825-832. doi: 10.1177/1526602817729673. Epub 2017 Sep 6.

Abstract

PURPOSE

To analyze the outcome of surgeon-modified fenestrated and branched stent-grafts (sm-FBSG) in high-risk patients with symptomatic complex aortic pathology or contained rupture.

METHODS

A single-center retrospective analysis was conducted of 21 consecutive patients (mean age 70 years, range 58-87; 16 men) treated with a sm-FBSG from April 2014 to September 2016. The indications included 11 thoracoabdominal and 10 pararenal aortic pathologies, which presented as symptomatic in 8 and as contained rupture in 13 patients. The mean aneurysm diameter was 7.4±2.3 cm.

RESULTS

Technical success was 100%. From 1 to 4 (mean 3) renovisceral branch vessels were targeted with fenestrations. The mean length of in-hospital stay was 19 days (range 1-78). There was 1 death within 30 days and 2 further in-hospital deaths. Two patients suffered permanent spinal cord injury, 2 developed respiratory failure, and 2 had renal failure requiring temporary or permanent dialysis. No myocardial infarction, stroke, or bowel ischemia occurred. Six early endoleaks (3 type II and 3 minor type III) were detected. Mean follow-up was 11.2 months (range 2-33) in 17 patients. One late aneurysm-related death occurred. All 13 follow-up imaging studies showed patent target renovisceral vessels, with 1 type I and 2 type II endoleaks.

CONCLUSION

Sm-FBSG can be utilized for urgent treatment of complex abdominal and thoracoabdominal aortic pathologies in high-risk patients with anatomy unsuitable for commercially available stent-grafts.

摘要

目的

分析外科改良开窗及分支型覆膜支架移植物(sm-FBSG)在有症状的复杂主动脉病变或局限性破裂的高危患者中的治疗效果。

方法

对2014年4月至2016年9月间连续接受sm-FBSG治疗的21例患者(平均年龄70岁,范围58 - 87岁;16例男性)进行单中心回顾性分析。适应证包括11例胸腹主动脉病变和10例肾旁主动脉病变;其中8例有症状,13例为局限性破裂。动脉瘤平均直径为7.4±2.3 cm。

结果

技术成功率为100%。开窗定位1至4支(平均3支)肾血管分支。平均住院时间为19天(范围1 - 78天)。30天内死亡1例,住院期间另有2例死亡。2例患者发生永久性脊髓损伤,2例出现呼吸衰竭,2例出现肾衰竭需临时或永久透析。未发生心肌梗死、中风或肠缺血。检测到6例早期内漏(3例II型和3例轻微III型)。17例患者平均随访11.2个月(范围2 - 33个月)。发生1例晚期动脉瘤相关死亡。所有13次随访影像学检查显示目标肾血管分支通畅,有1例I型和2例II型内漏。

结论

对于解剖结构不适合使用市售覆膜支架移植物的高危患者,sm-FBSG可用于紧急治疗复杂的腹主动脉和胸腹主动脉病变。

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