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BAT 人体研究中最常用的方程在估计年轻瘦男子皮肤温度参数方面的差异。

Differences between the most used equations in BAT-human studies to estimate parameters of skin temperature in young lean men.

机构信息

PROFITH "PROmoting FITness and Health through physical activity" research group. Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain.

Department of Medicine, Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

Sci Rep. 2017 Sep 5;7(1):10530. doi: 10.1038/s41598-017-10444-5.

DOI:10.1038/s41598-017-10444-5
PMID:28874709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5585347/
Abstract

Cold exposure is necessary to activate human brown adipose tissue (BAT), resulting in heat production. Skin temperature is an indirect measure to monitor the body's reaction to cold. The aim of this research was to study whether the most used equations to estimate parameters of skin temperature in BAT-human studies measure the same values of temperature in young lean men (n = 11: 23.4 ± 0.5 years, fat mass: 19.9 ± 1.2%). Skin temperature was measured with 26 ibuttons at 1-minute intervals in warm and cold room conditions. We used 12 equations to estimate parameters of mean, proximal, and distal skin temperature as well as skin temperature gradients. Data were analysed with Temperatus software. Significant differences were found across equations to measure the same parameters of skin temperature in warm and cold room conditions, hampering comparison across studies. Based on these findings, we suggest to use a set of 14 ibuttons at anatomical positions reported by ISO STANDARD 9886:2004 plus five ibuttons placed on the right supraclavicular fossa, right middle clavicular bone, right middle upper forearm, right top of forefinger, and right upper chest.

摘要

冷暴露对于激活人体棕色脂肪组织(BAT)和产热是必需的。皮肤温度是监测机体对寒冷反应的间接测量指标。本研究的目的是研究在年轻瘦人中,用于 BAT 人体研究中估计皮肤温度参数的最常用方程是否测量了相同的温度值(n=11:23.4±0.5 岁,脂肪量:19.9±1.2%)。在温暖和寒冷的房间条件下,使用 26 个 ibuttons 以 1 分钟的间隔测量皮肤温度。我们使用 12 个方程来估计平均、近端和远端皮肤温度以及皮肤温度梯度的参数。使用 Temperatus 软件对数据进行分析。在温暖和寒冷的房间条件下,测量相同皮肤温度参数的方程之间存在显著差异,这阻碍了研究之间的比较。基于这些发现,我们建议使用一套由 ISO 标准 9886:2004 报告的 14 个 ibuttons 加上 5 个位于右锁骨上窝、右锁骨中骨、右上臂中部、右食指顶部和右上胸部的 ibuttons。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/daa4ff02283b/41598_2017_10444_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/196a28290585/41598_2017_10444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/78d9d55682e7/41598_2017_10444_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/bcf649ffc312/41598_2017_10444_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/a9b441d96fee/41598_2017_10444_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/1a2f2d916c82/41598_2017_10444_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/daa4ff02283b/41598_2017_10444_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/196a28290585/41598_2017_10444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/78d9d55682e7/41598_2017_10444_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/bcf649ffc312/41598_2017_10444_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/a9b441d96fee/41598_2017_10444_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/1a2f2d916c82/41598_2017_10444_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f9a/5585347/daa4ff02283b/41598_2017_10444_Fig6_HTML.jpg

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