Schwartz Roy, Rozenberg Assaf, Loewenstein Anat, Goldstein Michaella
Ophthalmology Department, Tel Aviv Medical Center and The Sackler Faculty of Medicine, Tel Aviv University, 6 Weissman st, 64239, Tel Aviv, Israel.
Ophthalmology Department, Assaf Harofeh Medical Center and The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Graefes Arch Clin Exp Ophthalmol. 2017 Dec;255(12):2307-2315. doi: 10.1007/s00417-017-3787-6. Epub 2017 Sep 5.
To investigate a possible relationship between central serous chorioretinopathy (CSC) and specific body types and compositions (somatotypes), and to examine the cortisol stress response among CSC patients of different somatotypes in comparison with healthy subjects.
Prospective case-control study. A group of 28 patients with a previous or current diagnosis of CSC was compared with a group of 26 healthy subjects. Anthropometric measurements were used to estimate somatotype ratings in all subjects. Serum cortisol was measured at rest and following a stress-inducing computerized test in order to estimate response to stress in both groups. The main outcome measures included somatotype categorization and the change in serum cortisol following stress in both groups.
No significant difference in somatotype composition was found between the groups. There was no statistically significant difference between the groups in the elevation of cortisol following the stress-inducing test. The sample size was too small to exclude or find any significant difference between the different 13 subgroups of somatotype composition in the elevation of cortisol.
Our study did not show a typical somatotype related to CSC. While previous studies showed higher cortisol values in CSC patients, we did not see a higher elevation in blood cortisol following a stress response in this group in comparison with healthy subjects.
研究中心性浆液性脉络膜视网膜病变（CSC）与特定体型和身体成分（体型类型）之间可能存在的关系，并比较不同体型类型的CSC患者与健康受试者的皮质醇应激反应。
前瞻性病例对照研究。将一组28例既往或目前诊断为CSC的患者与一组26例健康受试者进行比较。采用人体测量学方法评估所有受试者的体型评分。在静息状态下以及进行应激诱导计算机测试后测量血清皮质醇，以评估两组的应激反应。主要观察指标包括体型分类以及两组应激后血清皮质醇的变化。
两组间体型组成无显著差异。在应激诱导测试后，两组间皮质醇升高情况无统计学显著差异。样本量过小，无法排除或发现体型组成的不同13个亚组在皮质醇升高方面的任何显著差异。
我们的研究未显示出与CSC相关的典型体型类型。虽然既往研究显示CSC患者的皮质醇值较高，但与健康受试者相比，我们在该组应激反应后未观察到血皮质醇有更高的升高。
