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伴有中心性浆液性脉络膜视网膜病变的眼睛的生物测量特征。

Biometric characteristics of eyes with central serous chorioretinopathy.

机构信息

Department of Ophthalmology, Ilsan Hospital, Dongguk University, Goyang, South Korea.

出版信息

Invest Ophthalmol Vis Sci. 2014 Mar 13;55(3):1502-8. doi: 10.1167/iovs.13-13183.

Abstract

PURPOSE

To investigate the biometric characteristics of eyes with idiopathic central serous chorioretinopathy (CSC).

METHODS

Medical records of 52 consecutive patients with unilateral CSC were reviewed. Central serous chorioretinopathy was diagnosed using spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography. Data collected for comparison with fellow eyes were refractive error, biometric measurements using partial coherence interferometry, and SD-OCT parameters.

RESULTS

Mean time from subjective symptom onset to initial visit was 8.3 ± 12.29 weeks. Mean axial length (AL) was shorter in CSC eyes than in fellow eyes by 0.24 ± 0.379 mm (P < 0.001), and mean anterior chamber depth (ACD) was shallower in CSC eyes than in fellow eyes by 0.03 ± 0.088 mm (P = 0.021). Central serous chorioretinopathy eyes also had thicker subfoveal choroidal thickness (CT) than fellow eyes by 34.0 ± 45.93 μm (P < 0.001). Differences in spherical equivalents between CSC and fellow eyes correlated with AL differences (r = -0.690, P < 0.001) and CT differences (r = 0.473, P = 0.001). On multiple linear regression analysis, the differences in ACD between CSC and fellow eyes were significantly correlated with AL differences (P = 0.032) and symptom duration (P = 0.019).

CONCLUSIONS

Biometric characteristics such as AL and ACD were different between eyes with CSC and fellow eyes. Variations in biometry, which correlated with CT differences, might be related to differences in refractive errors between eyes.

摘要

目的

研究特发性中心性浆液性脉络膜视网膜病变(CSC)患者的眼部生物测量学特征。

方法

回顾了 52 例单侧 CSC 连续患者的病历。通过谱域光相干断层扫描(SD-OCT)和荧光素血管造影诊断 CSC。与对侧眼比较,收集的资料包括屈光不正、使用部分相干干涉测量法进行的生物测量值以及 SD-OCT 参数。

结果

主观症状出现到首次就诊的平均时间为 8.3±12.29 周。CSC 眼的平均眼轴(AL)比对侧眼短 0.24±0.379mm(P<0.001),前房深度(ACD)比对侧眼浅 0.03±0.088mm(P=0.021)。CSC 眼的中心凹下脉络膜厚度(CT)比对侧眼厚 34.0±45.93μm(P<0.001)。CSC 眼与对侧眼的球镜屈光度差异与 AL 差异(r=-0.690,P<0.001)和 CT 差异(r=0.473,P=0.001)相关。多元线性回归分析显示,CSC 眼与对侧眼的 ACD 差异与 AL 差异(P=0.032)和症状持续时间(P=0.019)显著相关。

结论

CSC 眼与对侧眼的生物测量学特征如 AL 和 ACD 不同。与 CT 差异相关的生物测量学差异可能与眼间屈光不正差异有关。

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