Hamedi Nadya, da Costa Filipa Alves, Horne Robert, Levitan Michael, Begley Amanda, Antoniou Sotiris
St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
UCL Partners, 3rd Floor, 170 Tottenham Court Road, London, W1T 7HA, UK.
Int J Clin Pharm. 2017 Dec;39(6):1273-1281. doi: 10.1007/s11096-017-0529-0. Epub 2017 Sep 5.
Background The New Medicines Service (NMS) was implemented in the United Kingdom in 2011 and first evaluated in 2014, showing 10% increase on adherence. Objective To assess community pharmacists' current practice, knowledge and confidence in supporting patients' adherence as part of the NMS for patients on Oral Anti-Coagulants (OACs) for stroke prevention in Atrial Fibrillation. Setting Community pharmacists in London. Method An online cross-sectional survey was sent to pharmacists from their Local Pharmaceutical Committees and advertised by the Royal Pharmaceutical Society. Analysis was undertaken in SPSs v23 considering a confidence level of 95%. Main outcome measures pharmacists reported confidence of providing the NMS on OACs; training needs and skills for supporting adherence. Results A total of 257 valid responses were analysed (6.8% response rate; {Cronbach's α = 0.676-0.892}). Data indicates that over a 2-month period, 25% of pharmacists had completed ≥6 NMS consultations for all OACs, of which 11% for new oral anticoagulants (NOACs). The key priorities in counselling items during the NMS consultation were to discuss actions to take when bleeding occurs, followed by supporting adherence. Pharmacists were more confident in their knowledge, skills and access to resources for Vitamin-K Antagonists (VKAs) than for NOACs (p < 0.005). Results also highlight pharmacists' unfamiliarity with alert cards, lower for NOACs than VKAs (p < 0.001), albeit perceived as critically important. Half the sample mentioned to use the British National Formulary as information resource. Conclusion Results suggest the provision of NMS for NOACs is low. Supporting pharmacists with tailored education and adherence support might foster dissemination.
新药品服务(NMS)于2011年在英国实施,并于2014年首次进行评估,结果显示依从性提高了10%。目的:评估社区药剂师在作为心房颤动中风预防口服抗凝剂(OACs)患者的NMS一部分支持患者依从性方面的当前实践、知识和信心。地点:伦敦的社区药剂师。方法:通过当地药学委员会向药剂师发送在线横断面调查,并由皇家药学会进行宣传。在SPSS v23中进行分析,置信水平为95%。主要结局指标:药剂师报告提供OACs的NMS的信心;支持依从性的培训需求和技能。结果:共分析了257份有效回复(回复率6.8%;克朗巴哈α系数=0.676 - 0.892)。数据表明,在2个月的时间里,25%的药剂师完成了≥6次针对所有OACs的NMS咨询,其中11%针对新型口服抗凝剂(NOACs)。NMS咨询期间咨询项目的关键优先事项是讨论出血时应采取的行动,其次是支持依从性。药剂师对维生素K拮抗剂(VKAs)的知识、技能和获取资源的信心比对NOACs的信心更高(p < 0.005)。结果还突出了药剂师对警示卡不熟悉,NOACs的情况比VKAs更低(p < 0.001),尽管认为其至关重要。一半的样本提到使用《英国国家处方集》作为信息资源。结论:结果表明NOACs的NMS提供率较低。为药剂师提供量身定制的教育和依从性支持可能会促进其推广。