Chen Qiao, Guo Na, Xu Nan, Bao Gui-Hua
School of pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.
School of pharmacy, Inner Mongolia University for the Nationality, Tongliao 028000, China.
Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(5):864-867. doi: 10.4268/cjcmm20160517.
Eleven compounds were purified from the anti-inflammatory extract of Picris davurica by column chromatograph on HP20 macroporous resin, MCI, sephadex LH-20 and ODS.Their structures were determined by the spectra data of NMR and MS as isoestin 7-O-β-D-glucopyranosyl-2'-O-α-L-arabinopyranoside(1), isoetin-7-O-β-D-glucopyranosyl-2'-O-β-D-xyloypyranoside(2), isoetin-7-O-β-D-glucopyranosyl-2'-O-α-D-glucopy- ranoside(3), isoetin 5'-O-β-D-glucopyranoside(4), isoetin-2'-O-β-D-xyloypyranoside(5), isoetin-4'-O-β-D-O-β-D-glucopyranoside(6), isoetin-7-O-β-D-glucopyranoside(7), isoestin-2'-O-α-L-arabinopyranoside(8), luteolin-7-O-β-D-glucopyranosie(9), isoetin(10) and luteolin (11). All compounds were isolated from this plantfor the first time.Among them, compounds 1-8 were isolated from the genus Picris for the first time.
通过HP20大孔树脂、MCI、葡聚糖凝胶LH - 20和ODS柱色谱法从兴安漏芦的抗炎提取物中纯化出11种化合物。通过核磁共振（NMR）和质谱（MS）光谱数据确定它们的结构分别为异黄酮7 - O-β - D - 吡喃葡萄糖基 - 2'- O-α - L - 吡喃阿拉伯糖苷（1）、异黄酮7 - O-β - D - 吡喃葡萄糖基 - 2'- O-β - D - 吡喃木糖苷（2）、异黄酮7 - O-β - D - 吡喃葡萄糖基 - 2'- O-α - D - 吡喃葡萄糖苷（3）、异黄酮5'- O-β - D - 吡喃葡萄糖苷（4）、异黄酮2'- O-β - D - 吡喃木糖苷（5）、异黄酮4'- O-β - D - O-β - D - 吡喃葡萄糖苷（6）、异黄酮7 - O-β - D - 吡喃葡萄糖苷（7）、异黄酮2'- O-α - L - 吡喃阿拉伯糖苷（8）、木犀草素7 - O-β - D - 吡喃葡萄糖苷（9）、异黄酮（10）和木犀草素（11）。所有化合物均为首次从该植物中分离得到。其中，化合物1 - 8为首次从漏芦属植物中分离得到。
