Chen Fang-Fang, Zhang Yu-Wei, Huang Xue-Feng
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(6):976-988. doi: 10.4268/cjcmm20160602.
The genus Solanum which is the largest genus in Solanaceae consists of more than 2 000 species, most of them are distributed in tropics and subtropics areas, and only a small amount in temperate regions throughout the world. Steroidal saponins could be found in many species of the Solanum, and they are an important group of natural products exhbiting a number of potent beneficent properties, such as anti-tumor, antibacterial, antifungal, anti-inflammatory, antiviral, antioxidant, hypoglycemic, and antihyperlipidemic effects. As supplement, this paper gives a review of different structural categories of steroidal saponins and their pharmacological effects from the solanum plants over the past decade, and it is intended to provide a point of reference for further research on steroidal saponins in Solanum plants.
茄属是茄科中最大的属，由2000多种植物组成，它们大多分布在热带和亚热带地区，在全球温带地区只有少量分布。许多茄属植物中都能找到甾体皂苷，它们是一类重要的天然产物，具有多种强大的有益特性，如抗肿瘤、抗菌、抗真菌、抗炎、抗病毒、抗氧化、降血糖和降血脂作用。作为补充，本文综述了过去十年茄属植物中甾体皂苷的不同结构类别及其药理作用，旨在为茄属植物中甾体皂苷的进一步研究提供参考依据。
