Chandler Stephanie F, Fynn-Thompson Francis, Mah Douglas Y
a Department of Cardiology , Boston Children's Hospital , Boston , MA , USA.
b Department of Pediatrics , Harvard Medical School , Boston , MA , USA.
Expert Rev Cardiovasc Ther. 2017 Nov;15(11):853-861. doi: 10.1080/14779072.2017.1376655. Epub 2017 Sep 13.
Congenital complete heart block affects 1/15,000 live-born infants, predominantly due to atrioventricular nodal injury from maternal antibodies of mothers with systemic lupus erythermatosus or Sjogren's syndrome. The majority of these children will need a pacemaker implanted prior to becoming young adults. This article will review the various patient and technical factors that influence the type of pacemaker implanted, and the current literature on optimal pacing practices. Areas covered: A literature search was performed using PubMed, Embase and Web of Science. Data regarding epicardial versus transvenous implants, pacing-induced ventricular dysfunction, alternative pacing strategies (including biventricular pacing, left ventricular pacing, and His bundle pacing), and complications with pacemakers in the pediatric population were reviewed. Expert commentary: There are numerous pacing strategies available to children with congenital complete heart block. The risks and benefits of the initial implant should be weighed against the long-term issues inherent with a life-time of pacing.
先天性完全性心脏传导阻滞影响1/15000的活产婴儿,主要是由于患有系统性红斑狼疮或干燥综合征的母亲的母体抗体导致房室结损伤。这些儿童中的大多数在成年前需要植入起搏器。本文将综述影响所植入起搏器类型的各种患者因素和技术因素,以及关于最佳起搏实践的当前文献。涵盖领域:使用PubMed、Embase和科学网进行文献检索。回顾了关于心外膜植入与经静脉植入、起搏诱发的心室功能障碍、替代起搏策略(包括双心室起搏、左心室起搏和希氏束起搏)以及儿科人群起搏器并发症的数据。专家评论:对于先天性完全性心脏传导阻滞的儿童有多种起搏策略可用。初始植入的风险和益处应与终身起搏所固有的长期问题相权衡。