Goutham Kommuru, Kadiyala Veerabhushanam, Sridhar Balasubramanian, Karunakar Galla V
Crop Protection Chemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India.
Org Biomol Chem. 2017 Sep 26;15(37):7813-7818. doi: 10.1039/c7ob01285c.
An efficient gold-catalyzed synthetic protocol for the construction of 1,2-dihydro[c][2,7]naphthyridines from 2-aminophenyl prop-2-yn-1-yl enaminones has been developed. In this organic transformation new C-C and C-N bond formations occur via 6-endo-dig cyclization and condensation. 1,2-Dihydro[c][2,7]naphthyridine derivatives were obtained in good to excellent yields in a one-pot synthesis at ambient temperature.
已开发出一种高效的金催化合成方法，用于从2-氨基苯基丙-2-炔-1-基烯胺酮构建1,2-二氢[c][2,7]萘啶。在这种有机转化中，通过6-内型环化和缩合形成了新的C-C键和C-N键。在室温下一步合成中，以良好至优异的产率获得了1,2-二氢[c][2,7]萘啶衍生物。
