Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro , via Orabona 4, 70126 Bari, Italy.
Org Lett. 2017 Sep 15;19(18):4754-4757. doi: 10.1021/acs.orglett.7b02114. Epub 2017 Sep 6.
Direct arylation of 5-octylthieno[3,4-c]pyrrole-4,6-dione with a series of functionalized aryl iodides via C-H bond activation is demonstrated in a deep eutectic solvent made of choline chloride and urea in non-anhydrous conditions and without exclusion of air. This is the first demonstration of a thiophene-aryl coupling via direct arylation in deep eutectic solvents.
在非无水条件下，且无需排除空气的情况下，通过 C-H 键活化，在由氯化胆碱和尿素组成的深共熔溶剂中，实现了 5-辛基噻吩并[3,4-c]吡咯-4,6-二酮与一系列功能化芳基碘化物的直接芳基化。这是深共熔溶剂中通过直接芳基化实现噻吩-芳基偶联的首次展示。
