Simko Laura C, Espinoza Leda F, McMullen Kara, Herndon David N, Suman Oscar, Fauerbach James A, Kowalske Karen, Wiechman Shelley, Kazis Lewis E, Ryan Colleen M, Schneider Jeffrey C
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA.
Burn Model Systems National Data and Statistical Center, University of Washington, Seattle, WA.
J Burn Care Res. 2018 Apr 20;39(3):450-456. doi: 10.1097/BCR.0000000000000625.
Fatigue is a commonly reported but not well-documented symptom following burn injury. This study's objective was to determine the frequency and severity of fatigue over time and to identify predictors of fatigue in the adult burn population. Data from the Burn Model System National Database (April 1997 to January 2006) were analyzed. Individuals over 18 years of age who were alive at discharge were included. The vitality subscale of the Short-Form 36 Item Health Survey was examined at preinjury and discharge and at 6, 12, and 24 months postinjury. Mean and number of low vitality scores were calculated at each time interval. Descriptive statistics were generated for demographic and medical data. Cross-sectional regression models analyzed predictors of vitality at 6, 12, and 24 months postinjury. The study included 945 subjects. The population was 72.5% male and had a mean age of 40.6 years and mean burn size of 17.4%. Fatigue symptoms were present in a majority of the population (74.6%) and were most commonly reported at discharge. Although fewer burn survivors reported fatigue symptoms at each subsequent follow-up (P < .001), approximately one-half (49%) of the population continued to report fatigue symptoms at 24 months postinjury. Larger burn size was the only variable that was significant or approaching significance at all follow-up time points (P < .0167). Fatigue symptoms are common after burns and many burn survivors continue to report symptoms at 2 years postinjury. Burn survivors did not return to preinjury fatigue levels, highlighting the importance of understanding and monitoring fatigue.
疲劳是烧伤后常见但记录不充分的症状。本研究的目的是确定随时间推移疲劳的频率和严重程度，并识别成年烧伤人群中疲劳的预测因素。对烧伤模型系统国家数据库（1997年4月至2006年1月）的数据进行了分析。纳入出院时仍存活的18岁以上个体。在伤前、出院时以及伤后6个月、12个月和24个月对简短36项健康调查的活力子量表进行检查。计算每个时间间隔的低活力得分的平均值和数量。对人口统计学和医学数据进行描述性统计。采用横断面回归模型分析伤后6个月、12个月和24个月时活力的预测因素。该研究纳入了945名受试者。人群中72.5%为男性，平均年龄40.6岁，平均烧伤面积为17.4%。大多数人群（74.6%）存在疲劳症状，最常见于出院时报告。尽管在随后的每次随访中报告疲劳症状的烧伤幸存者较少（P < .001），但约一半（49%）的人群在伤后24个月仍报告有疲劳症状。烧伤面积较大是在所有随访时间点均显著或接近显著的唯一变量（P < .0167）。烧伤后疲劳症状常见，许多烧伤幸存者在伤后2年仍报告有症状。烧伤幸存者未恢复到伤前的疲劳水平，这凸显了了解和监测疲劳的重要性。
