• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

当今原发性高血压的治疗。β受体阻滞剂、钙拮抗剂及血管紧张素转换酶抑制剂的作用。

Treatment of essential hypertension today. The role of beta blockers, calcium antagonists, and ACE inhibitors.

作者信息

Lund-Johansen P

出版信息

Med Clin North Am. 1987 Sep;71(5):947-57. doi: 10.1016/s0025-7125(16)30819-7.

DOI:10.1016/s0025-7125(16)30819-7
PMID:2887720
Abstract

The greater sensitivity of echocardiography than electrocardiography has revealed left ventricular hypertrophy (LVH) to occur in a significant minority of patients with systemic hypertension, with the exact prevalence dependent both on how a population is selected and on the sex. race, and possibly age composition of its members. LVH is more closely related to blood pressure recorded in the patient's natural setting during normal activity or exercise--whether measured by portable recorder or home manometer--than to blood pressure measured by the physician. A subgroup of patients with mild essential hypertension exhibit high cardiac output and evidence of supernormal myocardial contractility in the absence of LVH; whereas amongst patients with more sustained hypertension, LVH may be either concentric (associated with high ejection fractions) or eccentric (associated with abnormal responses to exercise). Recent data indicate that echocardiographic detection of LVH identifies mildly hypertensive patients at significant risk, a finding that may aid identification of patients for drug treatment.

摘要

超声心动图比心电图具有更高的敏感性,这揭示了在相当一部分系统性高血压患者中会出现左心室肥厚(LVH),其确切患病率既取决于人群的选择方式,也取决于其成员的性别、种族,可能还有年龄构成。与医生测量的血压相比,LVH与患者在正常活动或运动期间自然状态下记录的血压关系更为密切,无论该血压是通过便携式记录仪还是家用血压计测量的。一小部分轻度原发性高血压患者表现出高心输出量以及在无LVH情况下心肌收缩力超常的证据;而在患有更持续性高血压的患者中,LVH可能是向心性的(与高射血分数相关)或离心性的(与运动异常反应相关)。最近的数据表明,超声心动图检测到的LVH可识别出有显著风险的轻度高血压患者,这一发现可能有助于识别适合药物治疗的患者。

相似文献

1
Treatment of essential hypertension today. The role of beta blockers, calcium antagonists, and ACE inhibitors.当今原发性高血压的治疗。β受体阻滞剂、钙拮抗剂及血管紧张素转换酶抑制剂的作用。
Med Clin North Am. 1987 Sep;71(5):947-57. doi: 10.1016/s0025-7125(16)30819-7.
2
Echocardiography, hypertension, and left ventricular mass.超声心动图、高血压与左心室质量
Health Psychol. 1988;7 Suppl:89-104. doi: 10.1037/h0090273.
3
Goals of antihypertensive therapy.抗高血压治疗的目标。
Drugs. 1995 Feb;49(2):161-75. doi: 10.2165/00003495-199549020-00002.
4
Left ventricular hypertrophy in hypertension. Prevalence and relationship to pathophysiologic variables.高血压中的左心室肥厚。患病率及其与病理生理变量的关系。
Hypertension. 1987 Feb;9(2 Pt 2):II53-60. doi: 10.1161/01.hyp.9.2_pt_2.ii53.
5
[Effects of calcium antagonist, angiotensin-converting enzyme inhibitors and beta-blocker on hemodynamic and sympathetic nerve responses to exercise in essential hypertension].[钙拮抗剂、血管紧张素转换酶抑制剂及β受体阻滞剂对原发性高血压患者运动时血流动力学及交感神经反应的影响]
J Cardiol. 1991;21(1):115-24.
6
Ischaemia and left ventricular hypertrophy.缺血与左心室肥厚。
Eur Heart J. 1993 Oct;14 Suppl F:2-6. doi: 10.1093/eurheartj/14.suppl_f.2.
7
Pathophysiology and clinical aspects of hypertensive hypertrophy.高血压性肥大的病理生理学与临床方面
Eur Heart J. 1993 Jul;14 Suppl D:2-7. doi: 10.1093/eurheartj/14.suppl_d.2.
8
A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta-blockers and diuretic agents on reactive hyperemia in patients with essential hypertension: a multicenter study.血管紧张素转换酶抑制剂、钙拮抗剂、β受体阻滞剂及利尿剂对原发性高血压患者反应性充血影响的比较:一项多中心研究
J Am Coll Cardiol. 2000 Feb;35(2):284-91. doi: 10.1016/s0735-1097(99)00561-6.
9
A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension.一项关于治疗对原发性高血压患者左心室质量影响的荟萃分析。
Am J Med. 2003 Jul;115(1):41-6. doi: 10.1016/s0002-9343(03)00158-x.
10
Use of digoxin, diuretics, beta blockers, angiotensin-converting enzyme inhibitors, and calcium channel blockers in older patients in an academic hospital-based geriatrics practice.在一家以学术医院为基础的老年医学实践中,老年患者使用地高辛、利尿剂、β受体阻滞剂、血管紧张素转换酶抑制剂和钙通道阻滞剂的情况。
J Am Geriatr Soc. 1997 Jul;45(7):809-12. doi: 10.1111/j.1532-5415.1997.tb01506.x.

引用本文的文献

1
Long-term hemodynamic effects of antihypertensive treatment.抗高血压治疗的长期血流动力学效应。
Clin Investig. 1992;70 Suppl 1:S58-64. doi: 10.1007/BF00207613.