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中东地区老年癌症趋势:黎巴嫩癌症预测研究至 2025 年的结果。

Geriatric cancer trends in the Middle-East: Findings from Lebanese cancer projections until 2025.

机构信息

Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

出版信息

J Geriatr Oncol. 2018 Mar;9(2):120-123. doi: 10.1016/j.jgo.2017.08.006. Epub 2017 Sep 4.

Abstract

OBJECTIVE

By 2020, 70% of all cancers will occur in patients aged 65years and older, causing an increase in related morbidity, mortality, and cost. This study projects cancer trends in the elderly population in Lebanon, a country experiencing accelerating aging trends. Findings will guide future policy decisions regarding geriatric oncology in Lebanon and the surrounding Arab world.

MATERIALS AND METHODS

Cancer incidence rates were derived for men and women 65years and above, divided into three age groups: 65-69years, 70-74years, and 75years and above. Raw data were obtained from the National Cancer Registry reports 2003-2010. The eight consecutive year data were used to project the incidence until 2025 using a logarithmic model. The Average Annual Percent Change in incidence rates was calculated to determine whether it would significantly increase, decrease, or remain stable over time.

RESULTS

Incidence rates are projected to increase significantly in all age groups of both genders until 2025. In men, the fastest rise is expected in prostate cancer, followed by bladder, lung, colorectal, and NHL. In women, the rise will be fastest in breast, followed by colorectal, lung, NHL, and ovary. Projected rates increase faster in the "younger" age group 65-69 compared to the "oldest" ≥75, both in men and women. Only kidney and liver cancers continue to rise significantly after 75.

CONCLUSIONS

Cancer incidence is projected to increase in individuals between 65 and 74years of age. Lebanese and Middle Eastern physicians must implement adapted therapeutic strategies in the management of the increasing caseload among frail, elderly patients.

摘要

目的

到 2020 年,所有癌症的 70%将发生在 65 岁及以上的患者中,导致发病率、死亡率和费用增加。本研究预测了黎巴嫩老年人群中的癌症趋势,该国老龄化趋势正在加速。研究结果将为未来黎巴嫩和周边阿拉伯世界老年肿瘤学的政策决策提供指导。

材料与方法

对 65 岁及以上的男性和女性的癌症发病率进行了研究,分为三个年龄组:65-69 岁、70-74 岁和 75 岁及以上。原始数据来自 2003-2010 年国家癌症登记报告。使用对数模型,将 8 年连续数据用于预测 2025 年的发病率。计算发病率的年均变化百分比,以确定其是否会随时间显著增加、减少或保持稳定。

结果

预计所有性别和年龄组的发病率在 2025 年前将显著增加。在男性中,前列腺癌预计上升最快,其次是膀胱癌、肺癌、结直肠癌和非霍奇金淋巴瘤。在女性中,乳腺癌的发病率上升最快,其次是结直肠癌、肺癌、非霍奇金淋巴瘤和卵巢癌。在男性和女性中,“较年轻”年龄组(65-69 岁)的预测增长率均快于“最年长”年龄组(≥75 岁)。只有肾癌和肝癌在 75 岁后仍继续显著上升。

结论

预计 65-74 岁人群的癌症发病率将上升。黎巴嫩和中东地区的医生必须在管理脆弱的老年患者不断增加的病例量方面实施适应性治疗策略。

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