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黎巴嫩的肾癌趋势和危险因素:一项 12 年的流行病学研究。

Kidney cancer trends and risk factors in Lebanon: a 12-year epidemiological study.

机构信息

Faculty of Medicine, Lebanese American University, Byblos, Lebanon.

Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.

出版信息

Cancer Causes Control. 2022 Feb;33(2):303-312. doi: 10.1007/s10552-021-01525-y. Epub 2021 Nov 28.

DOI:10.1007/s10552-021-01525-y
PMID:34839395
Abstract

PURPOSE

Lebanon has witnessed an increase in the rates of several cancer subtypes over the last years. The aim of this study is to examine the incidence rates of kidney cancer in Lebanon over 12 years and to compare them to other countries.

METHODS

Data were collected from the Lebanese National Cancer Registry (NCR) for the time period 2005-2016 (inclusive). Data from other countries were retrieved from an online database "Cancer Incidence in Five Continents." The age specific and age-standardized rates (ASR) were calculated and analyzed using Joinpoint regression.

RESULTS

Kidney cancer ranked as the 10th commonest cancer among men and the 19th among women. An age-standardized rate of 3.54 (per 100,000) was obtained. The average ASR was 4.80 for men and 2.27 for women. Kidney cancer showed a significantly rising trend for both genders. Lebanon had the highest ASR for kidney cancer in men and the third highest in women among regional countries.

CONCLUSION

Lebanon presented an average-to-high ASR for kidney cancer compared to regional countries. However, compared to countries worldwide, Lebanon had a below-average ASR. Nonetheless, with the rising kidney cancer trends, it is important to study the associated risk factors in order to develop proper preventive and screening measures and therefore decrease the incidence rates.

摘要

目的

近年来,黎巴嫩几种癌症亚型的发病率有所上升。本研究旨在研究 12 年来黎巴嫩肾癌的发病率,并将其与其他国家进行比较。

方法

数据来自黎巴嫩国家癌症登记处(NCR)2005-2016 年(含)期间的数据。其他国家的数据从在线数据库“五大洲癌症发病率”中检索。使用 Joinpoint 回归计算和分析年龄特异性和年龄标准化率(ASR)。

结果

肾癌在男性中排名第 10 位,在女性中排名第 19 位。获得了 3.54(每 100,000 人)的年龄标准化率。男性的平均 ASR 为 4.80,女性为 2.27。肾癌在两性中均呈明显上升趋势。黎巴嫩男性的肾癌年龄标准化率在该地区国家中最高,女性中排名第三。

结论

与该地区国家相比,黎巴嫩的肾癌年龄标准化率处于中高水平。然而,与全球各国相比,黎巴嫩的发病率处于平均水平以下。尽管如此,随着肾癌发病率的上升,研究相关的风险因素以制定适当的预防和筛查措施以降低发病率非常重要。

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