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下颌骨骨质消失病的一例罕见病例及文献综述

An unusual case of disappearing bone disease in the mandible and literature review.

作者信息

Naqvi Ambareen A, Joshi Sandeep S, Bailey Edmund

机构信息

Oral Surgery Department, Eastman Dental Hospital, London, UK.

出版信息

J Surg Case Rep. 2017 Feb 23;2017(2):rjx025. doi: 10.1093/jscr/rjx025. eCollection 2017 Feb.

DOI:10.1093/jscr/rjx025
PMID:28878876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5577639/
Abstract

Disappearing bone disease is a rare disorder that causes spontaneous and progressive osteolysis and proliferation of lymphatic tissue and blood vessels. It is debilitating and there is evidence of mortality in reported cases including those affecting mandible. A 38-year-old man was diagnosed with disappearing bone disease of the mandible in 2013. This had progressed from being in the right ramus only, and now extends to the lower right first molar and affects the left coronoid process and ramus. Mandibular involvement has shown to be high-risk. In older patients, misdiagnosis can occur without thorough investigation, and education of clinicians needs to be paramount to provide the appropriate treatment for this rare condition. The disease can be debilitating and as such education and support of patients is essential.

摘要

骨质溶解症是一种罕见的疾病,会导致自发性和进行性骨质溶解以及淋巴组织和血管增生。它会使人衰弱,在报告的病例中,包括那些影响下颌骨的病例,有死亡的证据。一名38岁男性在2013年被诊断为下颌骨骨质溶解症。病情已从仅累及右下颌支发展而来,现在已延伸至右下第一磨牙,并影响左冠状突和下颌支。下颌骨受累显示为高风险。在老年患者中,如果没有进行全面检查,可能会发生误诊,因此临床医生的培训对于为这种罕见疾病提供适当治疗至关重要。这种疾病会使人衰弱,因此对患者的教育和支持至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa57/5577639/658771a6669d/rjx025f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa57/5577639/658771a6669d/rjx025f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa57/5577639/658771a6669d/rjx025f01.jpg

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本文引用的文献

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American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update.美国口腔颌面外科医师协会关于药物相关性颌骨坏死的立场文件——2014年更新版
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2
Treatment of Gorham's disease with zoledronic acid.唑来膦酸治疗戈谢病。 (注:原文中“Gorham's disease”常见释义为“戈谢病”,但从专业角度更准确的是“ Gorham-Stout病”,这里按给定原文翻译)
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3
The anti-tumor potential of zoledronic acid.
唑来膦酸的抗肿瘤潜力。
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