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从台湾地区猫只分离出的猫免疫缺陷病毒的系统发育分析。

Phylogenetic analysis of feline immunodeficiency virus isolated from cats in Taiwan.

作者信息

Inada G, Miyazawa T, Inoshima Y, Kohmoto M, Ikeda Y, Liu C -H, Lin J A, Kou T -F, Mikami T

机构信息

Department of Veterinary Microbiology, Faculty of Agriculture, The University of Tokyo, Japan, Japan.

Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, Taiwan.

出版信息

Arch Virol. 1997 Jul;142(7):1459-1467. doi: 10.1007/s007050050172.

DOI:10.1007/s007050050172
PMID:28879401
Abstract

Feline immunodeficiency virus was isolated from four cats from Taiwan. The isolates were designated TI-1, TI-2, TI-3 and TI-4. Each was isolated from PBMCs following co-cultivation of PBMCs with a feline T-lymphoblastoid cell line (MYA-1 cells). However, the Taiwanese isolates did not grow in a feline kidney cell line (CRFK cells). The nucleotide sequences of the V3-V5 region of the envelope gene of the Taiwanese isolates were determined and compared with those of previously described isolates. Phylogenetic analysis of this region indicates that Taiwanese isolates belong to subtype C.

摘要

从台湾的四只猫身上分离出猫免疫缺陷病毒。这些分离株被命名为TI-1、TI-2、TI-3和TI-4。每株病毒都是在将外周血单核细胞(PBMCs)与猫T淋巴母细胞系(MYA-1细胞)共培养后从PBMCs中分离出来的。然而,台湾分离株在猫肾细胞系(CRFK细胞)中不能生长。测定了台湾分离株包膜基因V3-V5区域的核苷酸序列,并与先前描述的分离株进行了比较。该区域的系统发育分析表明,台湾分离株属于C亚型。

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Phylogenetic analysis of feline immunodeficiency virus isolated from cats in Taiwan.从台湾地区猫只分离出的猫免疫缺陷病毒的系统发育分析。
Arch Virol. 1997 Jul;142(7):1459-1467. doi: 10.1007/s007050050172.
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Phylogenetic analysis of feline immunodeficiency virus isolated from cats in Taiwan.从台湾地区猫只分离出的猫免疫缺陷病毒的系统发育分析。
Arch Virol. 1997;142(7):1459-67.
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Co-infection with different subtypes of feline immunodeficiency virus can complicate subtype assignment by phylogenetic analysis.猫免疫缺陷病毒不同亚型的合并感染会使系统发育分析的亚型分配复杂化。
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