Hamano Tsuyoshi, Shiotani Yoshiya, Takeda Miwako, Abe Takafumi, Sundquist Kristina, Nabika Toru
Department of Sports Sociology and Health Sciences, Faculty of Sociology, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555, Japan.
Department of Functional Pathology, Shimane University School of Medicine, 89-1 Enya-chou, Izumo, Shimane 693-8501, Japan.
Int J Environ Res Public Health. 2017 Sep 7;14(9):1022. doi: 10.3390/ijerph14091022.
Obesity is an established independent risk factor for developing hypertension. A recent study showed that the effect of obesity on hypertension varies by the elevation of the residence area. Thus, we hypothesized that the interaction effect of body mass index (BMI) and elevation has a significant association with hypertension. The first aim of this cross-sectional study was to examine whether BMI was associated with hypertension, after adjustment for covariates. The second aim was to examine whether the interaction term between BMI and elevation was associated with hypertension, after adjustment for covariates. Data were collected from a cross-sectional study conducted in a rural area of Japan in 2016. After excluding participants with missing data ( = 2), data from 729 participants were analyzed. We found that BMI was significantly associated with hypertension. In addition, the interaction term between BMI and elevation had a significant association with hypertension. The findings of the present study support the recent evidence that high BMI is an independent risk factor for hypertension, but its effect varies by elevation. Thus, context-specific interventions could be an effective approach to prevent hypertension in this area.
肥胖是公认的发生高血压的独立危险因素。最近一项研究表明，肥胖对高血压的影响因居住地区的海拔高度而异。因此，我们假设体重指数（BMI）与海拔高度的交互作用与高血压存在显著关联。这项横断面研究的首要目的是在调整协变量后，检验BMI是否与高血压相关。第二个目的是在调整协变量后，检验BMI与海拔高度的交互项是否与高血压相关。数据来自2016年在日本一个农村地区进行的横断面研究。在排除数据缺失的参与者（=2）后，对729名参与者的数据进行了分析。我们发现BMI与高血压显著相关。此外，BMI与海拔高度的交互项与高血压也存在显著关联。本研究结果支持了最近的证据，即高BMI是高血压的独立危险因素，但其影响因海拔高度而异。因此，因地制宜的干预措施可能是预防该地区高血压的有效方法。
