Bernasconi M, Voinea C, Hauser P M, Nicod L P, Lazor R
Division of Pulmonology, Ospedale Regionale di Bellinzona, Switzerland.
Division of Pulmonology, Lausanne University Hospital, Lausanne, Switzerland.
Respir Med Case Rep. 2017 Aug 24;22:215-217. doi: 10.1016/j.rmcr.2017.08.021. eCollection 2017.
is an anamorphic mould characterized by slow growth rate and production of a maroon pigment, which has been isolated worldwide from soil, thermal springs, decaying vegetation, and chicken litter. It has been reported to cause localized, mostly pulmonary, and systemic infection in severely immunocompromised patients. We describe the case of a 76-year-old woman known for ulcerative colitis-related bronchiectasis treated with low dose oral steroids, who developed a fungal bronchitis with dark, bloody-like, sputum which was initially misinterpreted as haemoptysis. A filamentary mould grew on sputum culture, and was identified by DNA analysis as . We observed a significant clinical improvement after 6 weeks of itraconazole therapy.
是一种变形霉菌，其特征为生长速度缓慢并产生栗色色素，已在全球范围内从土壤、温泉、腐烂植被和鸡粪中分离出来。据报道，它会在严重免疫功能低下的患者中引起局部感染，主要是肺部感染和全身感染。我们描述了一例76岁女性患者的病例，该患者因溃疡性结肠炎相关支气管扩张症接受低剂量口服类固醇治疗，她出现了真菌性支气管炎，痰液呈深色、类似血性，最初被误诊为咯血。痰培养长出一种丝状霉菌，经DNA分析鉴定为 。伊曲康唑治疗6周后，我们观察到患者临床症状有显著改善。
