Wolf R L, Gould N S, Green C A
Arch Pathol Lab Med. 1987 Oct;111(10):968-71.
A 5-year-old girl presented with a diffuse inflammatory disease that consisted of fever, lymphadenopathy, splenomegaly, and anterior uveitis. A chest x-ray film indicated an apparently nodular infiltrate. Her condition deteriorated abruptly, and she died of acute myocardial infarction. Autopsy revealed an extensive vasculitis that involved the aorta, pulmonary arteries, and coronary vessels. An aneurysm of the left coronary artery was noted. We present and discuss this case as an unusual arteritis in childhood, closely resembling Takayasu's disease. The presence of extensive erythrophagocytosis in sinus histiocytes hinted at a viral or immunologic origin for this child's disease.
一名5岁女孩出现一种弥漫性炎症性疾病，表现为发热、淋巴结病、脾肿大和前葡萄膜炎。胸部X线片显示有明显的结节状浸润。她的病情突然恶化，死于急性心肌梗死。尸检发现广泛的血管炎，累及主动脉、肺动脉和冠状动脉。发现左冠状动脉有一个动脉瘤。我们将此病例作为儿童期一种不寻常的动脉炎进行展示和讨论，它与高安氏病极为相似。窦组织细胞中存在广泛的红细胞吞噬现象提示该患儿疾病的病毒或免疫起源。
