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1999 - 2013年瑞典年轻女性中的抗抑郁药与自杀情况

Antidepressants and suicide among young women in Sweden 1999-2013.

作者信息

Larsson Jan

机构信息

Reporter/Researcher, Snöbollsgränd 22, 129 45 Hägersten, Sweden. E-mail:

出版信息

Int J Risk Saf Med. 2017;29(1-2):101-106. doi: 10.3233/JRS-170739.

Abstract

OBJECTIVE

To establish whether the young women (15-24 year old) who committed suicide in Sweden (1999-2013) received antidepressant treatment or not, and to what extent, prior to and/or at the time of suicide. To investigate the belief that increased prescription of antidepressants would drastically reduce the number of suicides.

METHODS

An analysis of data from the Swedish Prescribed Drug Register, the Causes of Death Register, with registers cross checked, and from the National Board of Forensic Medicine.

RESULTS

This analysis shows a covariance between increased prescription of antidepressants and an increasing trend in the number of suicides among young women. In the period 1999-2003 antidepressants were found in toxicological analyses done in 23% of the young women who committed suicide, and in 39% of cases for 2009-2013.

CONCLUSION

An increasingly larger proportion of young women who later committed suicide, had in the last few years been treated with antidepressants, prior to and at the time of the suicide. The previous assumptions that treatment with antidepressants would lead to a drastic reduction in suicide rates, are incorrect for the population of young women. On the contrary, it was found that an increasing tendency of completed suicides follow the increased prescription of antidepressants.

摘要

目的

确定在瑞典(1999 - 2013年)自杀的年轻女性(15 - 24岁)在自杀前和/或自杀时是否接受过抗抑郁治疗,以及接受治疗的程度。调查关于增加抗抑郁药处方量会大幅降低自杀人数的观点。

方法

对来自瑞典处方药登记册、死因登记册(进行登记册交叉核对)以及国家法医委员会的数据进行分析。

结果

该分析表明,抗抑郁药处方量的增加与年轻女性自杀人数的上升趋势之间存在协方差。在1999 - 2003年期间,在对自杀的年轻女性进行的毒理学分析中,23%的人被发现服用了抗抑郁药;在2009 - 2013年的案例中,这一比例为39%。

结论

在自杀前和自杀时,越来越大比例的后来自杀的年轻女性在过去几年中接受了抗抑郁药治疗。先前认为抗抑郁药治疗会导致自杀率大幅下降的假设,对于年轻女性群体来说是不正确的。相反,发现随着抗抑郁药处方量的增加,自杀既遂的趋势也在上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a5b/5611892/9dfed69d386b/jrs-29-jrs739-g001.jpg

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