Henriksson S, Boëthius G, Isacsson G
NEUROTEC, Division of Psychiatry, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden.
Acta Psychiatr Scand. 2001 Apr;103(4):301-6. doi: 10.1034/j.1600-0447.2001.00276.x.
This study presents data relating to prospectively monitored treatment and post-mortem toxicology of individuals who committed suicide.
A case-control study of prospectively monitored pharmacological treatment in suicides and controls. Psychiatric records and post-mortem toxicology were also studied.
Fifty-nine subjects who committed suicide purchased twice the number of prescriptions as the 118 controls. Sixteen cases received psychiatric in-patient care compared to four of the controls. In the last 3 months prior to suicide, 38 cases (64%) were dispensed drugs: anxiolytics-hypnotics in 17 cases (29%), antipsychotics in six cases (10%) and antidepressants in seven cases (12%). More psychiatrists than GPs prescribed antidepressants. About one-third of psychotropic drugs were retrieved in post-mortem toxicology.
There is a frequent use of psychotropics and psychiatric care among suicides; however, few used antidepressants and complied. Many suicides are still misdiagnosed and are not adequately treated.
本研究呈现了与自杀者前瞻性监测治疗及死后毒理学相关的数据。
一项对自杀者和对照者进行前瞻性监测药物治疗的病例对照研究。还研究了精神科记录和死后毒理学。
59名自杀者购买的处方数量是118名对照者的两倍。16例接受了精神科住院治疗，而对照者中有4例。在自杀前的最后3个月，38例（64%）被配药：17例（29%）使用抗焦虑 - 催眠药，6例（10%）使用抗精神病药，7例（12%）使用抗抑郁药。开抗抑郁药的精神科医生比全科医生多。死后毒理学检测中约三分之一的精神药物被检出。
自杀者中精神药物使用频繁且接受精神科护理；然而，使用抗抑郁药并遵医嘱的人很少。许多自杀者仍被误诊且未得到充分治疗。
