性别特异性与抑郁相关的疾病模块。
Sex-specific disease-associated modules for depression.
机构信息
Departments of Psychiatry and Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States.
出版信息
Nat Med. 2017 Sep 8;23(9):1015-1017. doi: 10.1038/nm.4391.
Abstract
A recent study reveals sexually dimorphic disease-associated gene-expression modules and hub genes in postmortem brains from female and male individuals with depression. These modules are conserved in mouse models of depression.
摘要
最近的一项研究揭示了在患有抑郁症的女性和男性死后大脑中存在性别二态性疾病相关的基因表达模块和枢纽基因。这些模块在抑郁症的小鼠模型中是保守的。
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