Graduate student, Department of Removable Prosthodontics & Gerodontology, Tokyo Dental College, Tokyo, Japan.
Associate Professor, Department of Removable Prosthodontics & Gerodontology, Tokyo Dental College, Tokyo, Japan.
J Prosthet Dent. 2018 Apr;119(4):663-670. doi: 10.1016/j.prosdent.2017.05.017. Epub 2017 Sep 6.
After oral cancer surgery, tissue defects can cause deformity and limited mobility, complicating many essential functions. For patients with mandibular, tongue, and oral floor defects, evidence regarding the effects of maxillofacial prosthetics on their oral health-related quality of life (OHRQoL) is lacking. Therefore, maxillofacial prosthetic reconstruction has been implemented with no clear treatment goals.
The purpose of this clinical study was to identify factors affecting the improvement of OHRQoL by using maxillofacial prosthetic treatment after surgery to repair maxillary, mandibular, tongue, and oral floor defects.
All individuals who agreed to maxillofacial prosthetics after surgery for oral cancer were enrolled. Oral function and OHRQoL were evaluated before maxillofacial prosthesis placement and 1 month after final adjustments. The oral functions evaluated included masticatory function, swallowing function, and articulatory function. The Oral Health Impact Profile (OHIP-J54) was used to evaluate OHRQoL. Factors affecting changes in the OHIP-J54 score for participants' background and oral functions before and after treatment were analyzed through logistic regression analysis (stepwise method).
Participants included 34 men and 16 women with an average age of 72.4 ±8.7 years. "Psychological discomfort" was correlated with the patient's sex and masticatory function. "Physical disability" was related to articulatory function. "Handicap" was related to the swallowing function. "Additional Japanese questions" were related to the patient's sex.
Participants' sex and their oral functions, including masticatory, swallowing, and articulatory functions, were associated with improved OHRQoL because of maxillofacial prosthetics after surgery for oral cancer.
口腔癌手术后，组织缺损会导致畸形和活动受限，从而影响许多重要的功能。对于下颌骨、舌和口腔底部缺损的患者，缺乏关于颌面修复体对其口腔健康相关生活质量（OHRQoL）影响的证据。因此，颌面修复体重建的实施缺乏明确的治疗目标。
本临床研究的目的是确定通过手术后使用颌面修复体治疗上颌骨、下颌骨、舌和口腔底部缺损来改善 OHRQoL 的影响因素。
所有同意在口腔癌手术后接受颌面修复体的患者均纳入本研究。在放置颌面修复体之前和最终调整后 1 个月评估口腔功能和 OHRQoL。评估的口腔功能包括咀嚼功能、吞咽功能和发音功能。使用口腔健康影响简表（OHIP-J54）评估 OHRQoL。通过逻辑回归分析（逐步法）分析参与者背景和治疗前后口腔功能对 OHIP-J54 评分变化的影响因素。
参与者包括 34 名男性和 16 名女性，平均年龄为 72.4±8.7 岁。“心理不适”与患者的性别和咀嚼功能相关。“生理障碍”与发音功能相关。“残障”与吞咽功能相关。“附加的日本问题”与患者的性别相关。
患者的性别和他们的口腔功能，包括咀嚼、吞咽和发音功能，与口腔癌手术后使用颌面修复体改善 OHRQoL 有关。
