Department of Psychology, Swansea University, Swansea, United Kingdom; Discipline of Psychiatry, and School of Psychology, University of Sydney, Sydney, Australia.
Section for Translational Psychobiology in Child and Adolescent Psychiatry, Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.
Neurosci Biobehav Rev. 2017 Dec;83:547-567. doi: 10.1016/j.neubiorev.2017.09.006. Epub 2017 Sep 6.
Heart rate variability (HRV) indexes functioning of the vagus nerve, arguably the most important nerve in the human body. The Neurovisceral Integration Model has provided a structural framework for understanding brain-body integration, highlighting the role of the vagus in adaptation to the environment. In the present paper, we emphasise a temporal framework in which HRV may be considered a missing, structural link between psychological moments and mortality, a proposal we label as Neurovisceral Integration Across a Continuum of Time (or NIACT). This new framework places neurovisceral integration on a dimension of time, highlighting implications for lifespan development and healthy aging, and helping to bridge the gap between clearly demarcated disciplines such as psychology and epidemiology. The NIACT provides a novel framework, which conceptualizes how everyday psychological moments both affect and are affected by the vagus in ways that have long-term effects on mortality risk. We further emphasize that a longitudinal approach to understanding change in vagal function over time may yield novel scientific insights and important public health outcomes.
心率变异性（HRV）指标可反映迷走神经的功能，迷走神经可以说是人体最重要的神经。神经生理整合模型为理解脑-体整合提供了一个结构框架，强调了迷走神经在适应环境中的作用。在本文中，我们强调了一个时间框架，在这个框架中，HRV 可以被视为心理时刻和死亡率之间缺失的结构性联系，我们将这个提议称为跨时间连续体的神经生理整合（Neurovisceral Integration Across a Continuum of Time，或 NIACT）。这个新框架将神经生理整合置于时间维度上，突出了其对寿命发展和健康老龄化的影响，并有助于弥合心理学和流行病学等明确界定的学科之间的差距。NIACT 提供了一个新颖的框架，概念化了日常心理时刻如何以长期影响死亡率风险的方式影响和受迷走神经的影响。我们进一步强调，采用纵向方法来理解随时间变化的迷走神经功能可能会产生新的科学见解和重要的公共卫生结果。
