Schulte Tobias L, Thielsch Meinald T, Gosheger Georg, Boertz Patrick, Terheyden Jan Henrik, Wetterkamp Mark
Department of Orthopedics and Trauma Surgery, Katholisches Klinikum Bochum, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
Department of Psychology, University of Münster, Münster, Germany.
Eur Spine J. 2018 Jan;27(1):83-92. doi: 10.1007/s00586-017-5284-3. Epub 2017 Sep 9.
The Quality of Life Profile for Spine Deformities (QLPSD) is a self-reporting questionnaire designed for studying patients with spinal deformities.
The aim of the present study was to systematically translate the QLPSD into German (G-QLPSD) and to test its reliability and validity. Special emphasis was intended to be given to patients with different Cobb angles and ages.
The QLPSD was systematically translated into German and was responded to in a web-based online survey by patients with idiopathic scoliosis and by healthy control individuals to carry out a matched-pair analysis. Participants aged 14 years and older were included. All participants answered a battery of validated questionnaires (SRS 22-r, PHQ-9, PANAS, FKS, WHO-5, BFI-S, PTQ). Reliability testing included Cronbach's alpha and test-retest reliability (retest 8 weeks after initial testing). Factorial, convergent, divergent, concurrent, and discriminant validity were calculated.
A total of 255 scoliosis patients (age 30.0 ± 16.7 years, Cobb angle 43.5° ± 20.9°) and 189 matched healthy control individuals were finally included. Cronbach's alpha for the G-QLPSD total score was 0.93 and the test-retest reliability was 0.84. The G-QLPSD total score correlated with the SRS 22-r total score (r = -0.86). All concurrently applied scores showed strong correlations with the G-QLPSD (e.g., depression score PHQ-9: r = 0.70). The matched-pair analysis of 189 pairs showed strong discriminant validity (Cohen's d = 0.78). Patients with more severe Cobb angles (≥40°) and those ≥18 years of age had significantly poorer results than patients with minor curves and younger patients.
The G-QLPSD proved to be a highly reliable and valid instrument that can be recommended for clinical use in scoliosis patients.
脊柱畸形生活质量概况问卷（QLPSD）是一份为研究脊柱畸形患者而设计的自填式问卷。
本研究旨在将QLPSD系统地翻译成德语（G-QLPSD），并测试其信度和效度。特别关注不同Cobb角和年龄的患者。
将QLPSD系统地翻译成德语，并通过基于网络的在线调查，让特发性脊柱侧凸患者和健康对照个体进行配对分析。纳入14岁及以上的参与者。所有参与者都回答了一系列经过验证的问卷（SRS 22-r、PHQ-9、PANAS、FKS、WHO-5、BFI-S、PTQ）。信度测试包括Cronbach's α系数和重测信度（初次测试8周后进行重测）。计算了因子效度、收敛效度、发散效度、同时效度和区分效度。
最终纳入了255例脊柱侧凸患者（年龄30.0±16.7岁，Cobb角43.5°±20.9°）和189例匹配的健康对照个体。G-QLPSD总分的Cronbach's α系数为0.93，重测信度为0.84。G-QLPSD总分与SRS 22-r总分相关（r = -0.86）。所有同时应用的分数与G-QLPSD均显示出强相关性（例如，PHQ-9抑郁评分：r = 0.70）。189对配对分析显示出强区分效度（Cohen's d = 0.78）。Cobb角更严重（≥40°）的患者和年龄≥18岁的患者的结果明显比轻度侧弯患者和年轻患者差。
G-QLPSD被证明是一种高度可靠且有效的工具，可推荐用于脊柱侧凸患者的临床应用。
