Garcia-Ruiz Hernan, Ruiz Mayra Teresa Garcia, Peralta Sergio Manuel Gabriel, Gabriel Cristina Betzabeth Miravel, El-Mounadi Kautar
Department of Plant Pathology, Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583 USA.
Universidad Autónoma Chapingo, México, CP 56230.
Rev Mex Fitopatol. 2016 May-Sep;34(3). doi: 10.18781/R.MEX.FIT.1606-8. Epub 2016 Sep 2.
Viral diseases of plants cause important economic losses due to reduction in crop quality and quantity to the point of threatening food security in some countries. Given the reduced availability of natural sources, genetic resistance to viruses has been successfully engineered for some plant-virus combinations. A sound understanding of the basic mechanisms governing plant-virus interactions, including antiviral RNA silencing, is the foundation to design better management strategies and biotechnological approaches to engineer and implement antiviral resistance in plants. In this review, we present current molecular models to explain antiviral RNA silencing and its application in basic plant research, biotechnology and genetic engineering.
植物病毒病会导致作物质量和产量下降，在某些国家甚至威胁到粮食安全，从而造成重大经济损失。鉴于天然资源日益减少，针对某些植物 - 病毒组合已成功培育出对病毒具有遗传抗性的植株。深入了解植物 - 病毒相互作用的基本机制，包括抗病毒RNA沉默，是设计更好的管理策略以及生物技术方法以培育和实现植物抗病毒抗性的基础。在本综述中，我们介绍了当前用于解释抗病毒RNA沉默及其在基础植物研究、生物技术和基因工程中的应用的分子模型。
