Centre for BioSystems, Institute of Phytopathology, Land Use and Nutrition, Justus Liebig University, Heinrich-Buff-Ring 26, D-35392 Giessen, Germany.
Viruses. 2019 Jul 23;11(7):673. doi: 10.3390/v11070673.
Viruses are obligate parasites which cause a range of severe plant diseases that affect farm productivity around the world, resulting in immense annual losses of yield. Therefore, control of viral pathogens continues to be an agronomic and scientific challenge requiring innovative and ground-breaking strategies to meet the demands of a growing world population. Over the last decade, RNA silencing has been employed to develop plants with an improved resistance to biotic stresses based on their function to provide protection from invasion by foreign nucleic acids, such as viruses. This natural phenomenon can be exploited to control agronomically relevant plant diseases. Recent evidence argues that this biotechnological method, called host-induced gene silencing, is effective against sucking insects, nematodes, and pathogenic fungi, as well as bacteria and viruses on their plant hosts. Here, we review recent studies which reveal the enormous potential that RNA-silencing strategies hold for providing an environmentally friendly mechanism to protect crop plants from viral diseases.
病毒是专性寄生的，会引起一系列严重的植物疾病，影响全球的农业生产力，导致巨大的年度产量损失。因此，控制病毒病原体仍然是一个农业和科学挑战，需要创新和突破性的策略来满足不断增长的世界人口的需求。在过去的十年中，RNA 沉默已被用于开发具有提高的抗生物胁迫能力的植物，其基于提供抵御外来核酸（如病毒）入侵的功能。这种自然现象可以被利用来控制具有农业意义的植物疾病。最近的证据表明，这种生物技术方法，称为寄主诱导的基因沉默，对吮吸昆虫、线虫和致病真菌以及其植物寄主上的细菌和病毒都有效。在这里，我们回顾了最近的研究，这些研究揭示了 RNA 沉默策略在为保护作物植物免受病毒病提供一种环保机制方面所具有的巨大潜力。
