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硬化性苔藓型闭塞性干燥性龟头炎致尿道狭窄病例中的阴茎鳞状细胞癌：一例报告并文献复习

Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature.

作者信息

Taneja Yogesh, Ram Priyatama, Dhaked Santosh Kumar, Sen Tridib Kumar

机构信息

DNB Trainee, Department of Urology, Sri Sathya Sai Institute of Higher Medical Sciences, Prashantigram, Ananthpur, Andhra Pradesh, India.

Senior Resident, Department of Anaesthesia, Sri Sathya Sai General Hospital, Prashantigram, Ananthpur, Andhra Pradesh, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):PD17-PD18. doi: 10.7860/JCDR/2017/26330.10254. Epub 2017 Jul 1.

DOI:10.7860/JCDR/2017/26330.10254
PMID:28892974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583896/
Abstract

Penile carcinoma is considered a delayed sequel of lichen sclerosus. It is important to recognize this not so uncommon complication in time as survival of patients with Squamous Cell Carcinoma (SCC) depends on early diagnosis and treatment. We describe a case of a 49-year-old male presenting with urethral stricture due to lichen sclerosus. He was treated for stricture disease and later on developed SCC penis after ten years of presentation.

摘要

阴茎癌被认为是硬化性苔藓的迟发性后遗症。及时认识到这种并非罕见的并发症很重要，因为鳞状细胞癌（SCC）患者的生存取决于早期诊断和治疗。我们描述了一例49岁男性因硬化性苔藓出现尿道狭窄的病例。他接受了狭窄疾病的治疗，在出现症状十年后发展为阴茎鳞状细胞癌。

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本文引用的文献

1
EAU guidelines on penile cancer: 2014 update.EAU 指南：阴茎癌 2014 年更新版
Eur Urol. 2015 Jan;67(1):142-150. doi: 10.1016/j.eururo.2014.10.017. Epub 2014 Nov 1.
2
Penile lichen sclerosus (balanitis xerotica obliterans).阴茎硬化性苔藓（干燥性闭塞性龟头炎）。
BJU Int. 2011 Nov;108 Suppl 2:14-9. doi: 10.1111/j.1464-410X.2011.10699.x.
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Is the association between balanitis xerotica obliterans and penile carcinoma underestimated?闭塞性干燥性龟头炎与阴茎癌之间的关联是否被低估了？
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Penile carcinoma in patients with genital lichen sclerosus: a multicenter survey.患有生殖器硬化性苔藓患者的阴茎癌：一项多中心调查。
J Urol. 2006 Apr;175(4):1359-63. doi: 10.1016/S0022-5347(05)00735-4.
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High incidence of lichen sclerosus in patients with squamous cell carcinoma of the penis.阴茎鳞状细胞癌患者中硬化性苔藓的高发病率。
Br J Dermatol. 2001 Jul;145(1):85-9. doi: 10.1046/j.1365-2133.2001.04287.x.
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Does lichen sclerosus play a central role in the pathogenesis of human papillomavirus negative vulvar squamous cell carcinoma? The itch-scratch-lichen sclerosus hypothesis.硬化性苔藓在人乳头瘤病毒阴性的外阴鳞状细胞癌发病机制中起核心作用吗？瘙痒-搔抓-硬化性苔藓假说。
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The treatment of balanitis xerotica obliterans.闭塞性干燥性龟头炎的治疗
BJU Int. 2000 Sep;86(4):459-65. doi: 10.1046/j.1464-410x.2000.00772.x.
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Penile cancer among patients with genital lichen sclerosus.患有生殖器硬化性苔藓的患者中的阴茎癌
J Am Acad Dermatol. 1999 Dec;41(6):911-4. doi: 10.1016/s0190-9622(99)70245-8.
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Lichen sclerosus.硬化性苔藓
Lancet. 1999 May 22;353(9166):1777-83. doi: 10.1016/s0140-6736(98)08228-2.
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Lichen sclerosus et atrophicus. Findings after complete circumcision.
Scand J Urol Nephrol. 1997 Oct;31(5):453-6. doi: 10.3109/00365599709030641.