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机器人辅助二尖瓣手术的早期结果:1000 例病例分析。

Early results of robotically assisted mitral valve surgery: Analysis of the first 1000 cases.

机构信息

Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

出版信息

J Thorac Cardiovasc Surg. 2018 Jan;155(1):82-91.e2. doi: 10.1016/j.jtcvs.2017.07.037. Epub 2017 Aug 1.

DOI:10.1016/j.jtcvs.2017.07.037
PMID:28893396
Abstract

OBJECTIVE

The study objective was to assess the technical and process improvement and clinical outcomes of robotic mitral valve surgery by examining the first 1000 cases performed in a tertiary care center.

METHODS

We reviewed the first 1000 patients (mean age, 56 ± 10 years) undergoing robotic primary mitral valve surgery, including concomitant procedures (n = 185), from January 2006 to November 2013. Mitral valve disease cause was degenerative (n = 960, 96%), endocarditis (n = 26, 2.6%), rheumatic (n = 10, 1.0%), ischemic (n = 3, 0.3%), and fibroelastoma (n = 1, 0.1%). All procedures were performed via right chest access with femoral perfusion for cardiopulmonary bypass.

RESULTS

Mitral valve repair was attempted in 997 patients (2 planned replacements and 1 resection of fibroelastoma), 992 (99.5%) of whom underwent valve repair, and 5 (0.5%) of whom underwent valve replacement. Intraoperative postrepair echocardiography showed that 99.7% of patients receiving repair (989/992) left the operating room with no or mild mitral regurgitation, and predischarge echocardiography showed that mitral regurgitation remained mild or less in 97.9% of patients (915/935). There was 1 hospital death (0.1%), and 14 patients (1.4%) experienced a stroke; stroke risk declined from 2% in the first 500 patients to 0.8% in the second 500 patients. Over the course of the experience, myocardial ischemic and cardiopulmonary bypass times (P < .0001), transfusion (P = .003), and intensive care unit and postoperative lengths of stay (P < .05) decreased.

CONCLUSIONS

Robotic mitral valve surgery is associated with a high likelihood of valve repair and low operative mortality and morbidity. The combination of algorithm-driven patient selection and increased experience enhanced clinical outcomes and procedural efficiency.

摘要

目的

本研究旨在评估在一家三级医疗中心实施的前 1000 例机器人二尖瓣手术的技术和流程改进以及临床结果。

方法

我们回顾了 2006 年 1 月至 2013 年 11 月期间前 1000 例(平均年龄 56 ± 10 岁)接受机器人二尖瓣手术的患者,包括同期手术(n = 185)。二尖瓣疾病的病因包括退行性(n = 960,96%)、感染性心内膜炎(n = 26,2.6%)、风湿性(n = 10,1.0%)、缺血性(n = 3,0.3%)和纤维弹性瘤(n = 1,0.1%)。所有手术均通过右胸入路和股动脉灌注进行体外循环。

结果

997 例患者尝试二尖瓣修复(2 例计划更换,1 例切除纤维弹性瘤),992 例(99.5%)接受了瓣膜修复,5 例(0.5%)接受了瓣膜置换。术中修复后超声心动图显示,99.7%(989/992)接受修复的患者术后无或轻度二尖瓣反流,出院前超声心动图显示,97.9%(915/935)的患者二尖瓣反流仍为轻度或以下。有 1 例院内死亡(0.1%),14 例(1.4%)发生脑卒中;脑卒中风险从第 500 例的 2%降至第 1000 例的 0.8%。在整个经验过程中,心肌缺血和体外循环时间(P < 0.0001)、输血(P = 0.003)以及重症监护病房和术后住院时间(P < 0.05)均有所降低。

结论

机器人二尖瓣手术与瓣膜修复的高可能性和较低的手术死亡率和发病率相关。基于算法的患者选择和经验的增加相结合,提高了临床结果和手术效率。

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