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抵达欧盟/欧洲经济区的儿童和成年移民中传染病的预防与评估:一套公共卫生与卫生系统系统评价方案

Prevention and assessment of infectious diseases among children and adult migrants arriving to the European Union/European Economic Association: a protocol for a suite of systematic reviews for public health and health systems.

作者信息

Pottie Kevin, Mayhew Alain D, Morton Rachael L, Greenaway Christina, Akl Elie A, Rahman Prinon, Zenner Dominik, Pareek Manish, Tugwell Peter, Welch Vivian, Meerpohl Joerg, Alonso-Coello Pablo, Hui Charles, Biggs Beverley-Ann, Requena-Méndez Ana, Agbata Eric, Noori Teymur, Schünemann Holger J

机构信息

Departments of Family Medicine, and Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.

C.T. Lamont Primary Health Care Research Centre, Bruyère Research Institute, Ottawa, Ontario, Canada.

出版信息

BMJ Open. 2017 Sep 11;7(9):e014608. doi: 10.1136/bmjopen-2016-014608.

Abstract

INTRODUCTION

The European Centre for Disease Prevention and Control is developing evidence-based guidance for voluntary screening, treatment and vaccine prevention of infectious diseases for newly arriving migrants to the European Union/European Economic Area. The objective of this systematic review protocol is to guide the identification, appraisal and synthesis of the best available evidence on prevention and assessment of the following priority infectious diseases: tuberculosis, HIV, hepatitis B, hepatitis C, measles, mumps, rubella, diphtheria, tetanus, pertussis, poliomyelitis (polio), disease, strongyloidiasis and schistosomiasis.

METHODS AND ANALYSIS

The search strategy will identify evidence from existing systematic reviews and then update the effectiveness and cost-effectiveness evidence using prospective trials, economic evaluations and/or recently published systematic reviews. Interdisciplinary teams have designed logic models to help define study inclusion and exclusion criteria, guiding the search strategy and identifying relevant outcomes. We will assess the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

ETHICS AND DISSEMINATION

There are no ethical or safety issues. We anticipate disseminating the findings through open-access publications, conference abstracts and presentations. We plan to publish technical syntheses as GRADEpro evidence summaries and the systematic reviews as part of a special edition open-access publication on refugee health. We are following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Protocols reporting guideline. This protocol is registered in PROSPERO: CRD42016045798.

摘要

引言

欧洲疾病预防控制中心正在为新抵达欧盟/欧洲经济区的移民制定关于传染病自愿筛查、治疗和疫苗预防的循证指南。本系统评价方案的目的是指导识别、评估和综合关于以下重点传染病预防和评估的最佳现有证据:结核病、艾滋病毒、乙型肝炎、丙型肝炎、麻疹、腮腺炎、风疹、白喉、破伤风、百日咳、脊髓灰质炎(小儿麻痹症)、盘尾丝虫病、类圆线虫病和血吸虫病。

方法与分析

检索策略将从现有的系统评价中识别证据,然后使用前瞻性试验、经济评估和/或最近发表的系统评价更新有效性和成本效益证据。跨学科团队设计了逻辑模型,以帮助确定研究的纳入和排除标准,指导检索策略并确定相关结果。我们将使用推荐分级评估、制定和评价(GRADE)方法评估证据的确定性。

伦理与传播

不存在伦理或安全问题。我们预计将通过开放获取出版物、会议摘要和报告来传播研究结果。我们计划将技术综合内容发表为GRADEpro证据摘要,并将系统评价作为关于难民健康的开放获取特刊的一部分发表。我们遵循系统评价和Meta分析的首选报告项目(PRISMA)方案报告指南。本方案已在国际前瞻性系统评价注册库(PROSPERO)注册:CRD42016045798。

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