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现实生活研究中生物可吸收血管支架失败的发生与处理

Occurrence and management of bioresorbable vascular scaffold failure in real-life studies.

作者信息

Cortese Bernardo, Elwany Mostafa

机构信息

Interventional Cardiology, ASST Fatebenefratelli Sacco, Milano, Italy.

Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Massa, Italy.

出版信息

J Thorac Dis. 2017 Aug;9(Suppl 9):S935-S939. doi: 10.21037/jtd.2017.06.82.

DOI:10.21037/jtd.2017.06.82
PMID:28894599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583083/
Abstract

Bioresorbable vascular scaffold (BVS) has emerged as a new technology aiming at overcoming some drawbacks of the conventional metallic stent. In spite of the initial promising results, this technology stumbled upon numerous challenges, which were revealed in the real world studies. Thanks to real world trials and registries findings, our knowledge about the BVS has grown over time, thus we have understood on BVS behavior in various settings and formulated better implantation techniques. In this article, we will review the incidence of BVS failure in real world studies, its different etiologies and management strategies.

摘要

生物可吸收血管支架（BVS）已成为一项旨在克服传统金属支架某些缺点的新技术。尽管最初取得了令人鼓舞的结果，但这项技术在现实世界研究中遇到了众多挑战。得益于现实世界试验和注册研究的结果，我们对BVS的了解随着时间的推移不断增加，因此我们已经了解了BVS在各种情况下的表现，并制定了更好的植入技术。在本文中，我们将回顾现实世界研究中BVS失败的发生率、其不同病因及管理策略。

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本文引用的文献

1
First experience of drug-coated balloons for treatment of bioresorbable vascular scaffold restenosis.药物涂层球囊治疗生物可吸收血管支架再狭窄的首次经验。
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Restenosis of Coronary Bioresorbable Vascular Scaffolds.冠状动脉生物可吸收血管支架再狭窄
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Very Late Scaffold Thrombosis of Bioresorbable Vascular Scaffold: Systematic Review and a Meta-Analysis.生物可吸收血管支架的极晚期支架血栓：系统评价和荟萃分析。
JACC Cardiovasc Interv. 2017 Jan 9;10(1):27-37. doi: 10.1016/j.jcin.2016.10.027.
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First reported use of drug-coated balloon for bioresorbable in-scaffold restenosis.首次报道使用药物涂层球囊治疗生物可吸收支架内再狭窄。
Catheter Cardiovasc Interv. 2017 Mar 1;89(4):676-678. doi: 10.1002/ccd.26803. Epub 2016 Sep 21.
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Overview of the 2016 U.S. Food and Drug Administration Circulatory System Devices Advisory Panel Meeting on the Absorb Bioresorbable Vascular Scaffold System.2016 年美国食品和药物管理局循环系统设备顾问小组会议概述：Absorb 生物可吸收血管支架系统。
JACC Cardiovasc Interv. 2016 Sep 12;9(17):1757-64. doi: 10.1016/j.jcin.2016.06.027.
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The Contemporary Pulse of Bioresorbable-Scaffold Thrombosis Among Expert Operators.
J Am Coll Cardiol. 2016 Jun 21;67(24):2905-6. doi: 10.1016/j.jacc.2016.03.576.
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Platelet reactivity over time in coronary artery disease patients treated with a bioabsorbable everolimus-eluting scaffold.
Platelets. 2016 Dec;27(8):777-783. doi: 10.1080/09537104.2016.1184750. Epub 2016 Jun 2.
10
Impact of the bioresorbable vascular scaffold surface area on on-treatment platelet reactivity.
Platelets. 2016 Jul;27(5):446-51. doi: 10.3109/09537104.2016.1143918. Epub 2016 Mar 4.