Merrill Robert K, Kim Jun S, Leven Dante M, Kim Joung Heon, Cho Samuel K
Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Global Spine J. 2017 Sep;7(6):514-520. doi: 10.1177/2192568217699392. Epub 2017 Apr 11.
Retrospective cohort study.
To determine if patients fused with multi-rod constructs to the pelvis have a lower incidence of lumbosacral rod failure and pseudarthrosis than those fused with dual-rod constructs.
We performed a retrospective review of consecutive adult spinal deformity patients who underwent long fusion to the pelvis. Inclusion criteria were >5 levels, primary fusion or revision for L5-S1 pseudarthrosis, and minimum 1-year follow-up. Revision patients with indications other than L5-S1 pseudarthrosis were excluded. One-year follow-up plain radiographs were reviewed for rod integrity, and computed tomography scan (CT) was obtained whenever rod breakage was observed. Dual-rod and multi-rod (3 or 4 rods) cohorts were statistically compared.
There were 31 patients with 15 in the dual-rod group and 16 in the multi-rod group, with average ages of 68 ± 9 and 63 ± 12 years, respectively. No patients in the multi-rod group experienced rod fracture, whereas 6 in the dual-rod group fractured a rod ( = .007), with 4 occurring at the lumbosacral junction ( = .04). CT scan in the 4 lumbosacral rod fracture cases, and surgical exploration in 3, confirmed pseudarthrosis and hypertrophic nonunion at the L5-S1 junction.
Patients with dual-rod constructs had a statistically greater incidence of lumbosacral pseudarthrosis with implant failure than those with multi-rod constructs. CT and surgical exploration showed hypertrophic nonunion as opposed to oligo- or atrophic nonunion. This suggests that mechanical instability, not biology, is the main reason for failure, and could be addressed with the use of multi-rods.
回顾性队列研究。
确定与采用双棒结构融合至骨盆的患者相比,采用多棒结构融合至骨盆的患者腰骶部棒材失效和假关节形成的发生率是否更低。
我们对连续接受长节段融合至骨盆的成人脊柱畸形患者进行了回顾性研究。纳入标准为融合节段>5个、L5-S1假关节的初次融合或翻修,以及至少1年的随访。排除具有L5-S1假关节以外指征的翻修患者。对1年随访时的平片进行棒材完整性评估,一旦观察到棒材断裂,则进行计算机断层扫描(CT)检查。对双棒组和多棒组(3或4根棒)进行统计学比较。
共有31例患者,双棒组15例,多棒组16例,平均年龄分别为68±9岁和63±12岁。多棒组无患者发生棒材骨折,而双棒组有6例棒材骨折(P = 0.007),其中4例发生在腰骶部交界处(P = 0.04)。4例腰骶部棒材骨折病例的CT扫描以及3例手术探查证实了L5-S1交界处的假关节形成和肥大性骨不连。
与采用多棒结构的患者相比,采用双棒结构的患者腰骶部假关节合并植入物失效的发生率在统计学上更高。CT和手术探查显示为肥大性骨不连,而非少或萎缩性骨不连。这表明机械不稳定而非生物学因素是失败的主要原因,使用多棒结构可能解决该问题。