James Cornelius A, Gonzalez Ismael, Khandhar Paras, Freij Bishara J
Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Beaumont Children's Hospital, Royal Oak, MI, USA.
Glob Pediatr Health. 2017 Sep 1;4:2333794X17726940. doi: 10.1177/2333794X17726940. eCollection 2017.
Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. The classic triad of HSP consists of nonthrombocytopenic purpura, arthritis/arthralgia, and gastrointestinal complaints. Pulmonary hemorrhage and cardiac involvement are rare complications of HSP. : We report the case of a 10-year-old girl with HSP complicated by both severe mitral regurgitation and pulmonary hemorrhage. : HSP is typically a self-limited illness with an excellent prognosis in children. Pulmonary hemorrhage is a rare complication that increases morbidity and mortality; it generally indicates the presence of severe vasculitis. Cardiac involvement in HSP is extremely rare and associated with a poor prognosis. : Cardiac involvement in HSP may be more common than believed. Because of the increased morbidity and mortality associated with HSP complicated by pulmonary hemorrhage and cardiac involvement, it is important for clinicians to be aware of these potential complications.
过敏性紫癜（HSP）是儿童期最常见的血管炎。HSP的典型三联征包括非血小板减少性紫癜、关节炎/关节痛和胃肠道症状。肺出血和心脏受累是HSP的罕见并发症。我们报告一例10岁患过敏性紫癜并发严重二尖瓣反流和肺出血的女孩病例。过敏性紫癜通常是一种自限性疾病，儿童预后良好。肺出血是一种罕见的并发症，会增加发病率和死亡率；它通常表明存在严重的血管炎。HSP累及心脏极为罕见且预后不良。HSP累及心脏可能比人们认为的更常见。由于HSP并发肺出血和心脏受累会增加发病率和死亡率，临床医生了解这些潜在并发症很重要。
