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影响盆腔器官脱垂手术结局的因素。

Factors influencing the outcome of surgery for pelvic organ prolapse.

作者信息

Bohlin Katja Stenström, Ankardal Maud, Nüssler Emil, Lindkvist Håkan, Milsom Ian

机构信息

Department of Obstetrics and Gynecology, Sahlgrenska Academy at Gothenburg University, SE-416 85, Gothenburg, Sweden.

Department of Gynecology, Halland Hospital, Halmstad, Sweden.

出版信息

Int Urogynecol J. 2018 Jan;29(1):81-89. doi: 10.1007/s00192-017-3446-9. Epub 2017 Sep 11.

Abstract

INTRODUCTION AND HYPOTHESIS

Pelvic organ prolapse (POP) surgery is a common gynecological procedure. Our aim was to assess the influence of obesity and other risk factors on the outcome of anterior and posterior colporrhaphy with and without mesh.

METHODS

Data were retrieved from the Swedish National Register for Gynecological Surgery on 18,554 women undergoing primary and repeat POP surgery without concomitant urinary incontinence (UI) surgery between 2006 and 2015. Multivariate logistic regression analyses were used to identify independent risk factors for a sensation of a vaginal bulge, de novo UI, and residual UI 1 year after surgery.

RESULTS

The overall subjective cure rate 1 year after surgery was 80% (with mesh 86.4% vs 77.3% without mesh, p < 0.001). The complication rate was low, but was more frequent in repeat surgery that were mainly mesh related. The use of mesh was also associated with more frequent de novo UI, but patient satisfaction and cure rates were higher compared with surgery without mesh. Preoperative sensation of a vaginal bulge, severe postoperative complications, anterior colporrhaphy, prior hysterectomy, postoperative infections, local anesthesia, and body mass index (BMI) ≥30 were risk factors for sensation of a vaginal bulge 1 year postsurgery. Obesity had no effect on complication rates but was associated increased urinary incontinence (UI) after primary surgery. Obesity had no influence on cure or voiding status in women undergoing repeat surgery.

CONCLUSIONS

Obesity had an impact on the sensation of a vaginal bulge and the presence of UI after primary surgery but not on complications.

摘要

引言与假设

盆腔器官脱垂(POP)手术是一种常见的妇科手术。我们的目的是评估肥胖及其他风险因素对有或无网片的前后壁修补术结果的影响。

方法

从瑞典国家妇科手术登记处检索了2006年至2015年间18554例接受初次及再次POP手术且未同时进行尿失禁(UI)手术的女性的数据。采用多因素逻辑回归分析确定术后1年出现阴道膨出感、新发UI和残余UI的独立危险因素。

结果

术后1年的总体主观治愈率为80%(使用网片为86.4%,未使用网片为77.3%,p<0.001)。并发症发生率较低,但在主要与网片相关的再次手术中更常见。使用网片还与更频繁的新发UI相关,但与无网片手术相比,患者满意度和治愈率更高。术前阴道膨出感、严重术后并发症、前壁修补术、既往子宫切除术、术后感染、局部麻醉和体重指数(BMI)≥30是术后1年阴道膨出感的危险因素。肥胖对并发症发生率无影响,但与初次手术后尿失禁(UI)增加有关。肥胖对接受再次手术的女性的治愈率或排尿状态无影响。

结论

肥胖对初次手术后的阴道膨出感和尿失禁的存在有影响,但对并发症无影响。

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