Evaluation of Normative Data of a Widely Used Computerized Neuropsychological Battery: Applicability and Effects of Sociodemographic Variables in a Dutch Sample.

Central Nervous System Vital Signs (CNS VS) is a computerized neuropsychological battery that is translated into many languages. However, published CNS VS' normative data were established over a decade ago, are solely age-corrected, and collected in an American population only. Mean performance of healthy Dutch participants on CNS VS was compared with the original CNS VS norms ( = 1,069), and effects of sociodemographic variables were examined. tests demonstrated no significant differences in performance on four out of seven cognitive domains; however, Dutch participants ( = 158) showed higher scores on processing and psychomotor speed, as well as on cognitive flexibility. Although the original CNS VS norms are solely age-corrected, effects of education and sex on CNS VS performance were also identified in the Dutch sample. Users should be cautious when interpreting CNS VS performance based on the original American norms, and sociodemographic factors must also be considered.