Fedorov V I
Fiziol Zh SSSR Im I M Sechenova. 1987 Jul;73(7):913-9.
In anesthetized rats, 1938 blood pressure (BP) responses to i.v. injections of angiotensin II were studied. 6 types and 21 subtypes of responses were distinguished: vasopressor response followed by BP normalizing (type 1; 42%) or by a transitory BP drop (type 2; 7%); BP elevation without its subsequent decrease (type 3; 3%) preliminary sharp increase of BP followed by a "classic" angiotensin pressor effect (type 4; 3%); biphasic response--a depressor response followed by a pressor one (type 5; 27%); depressor response alone (type 6; 18%). Depressor phases were increased by phentolamine and indomethacin, and were inhibited by atropine and spasmolytin. The responses to angiotensin II seem to have a vector character, cholinergic system attenuating this response.
在麻醉大鼠中，研究了1938次静脉注射血管紧张素II后的血压（BP）反应。区分出6种类型和21种亚型的反应：血管升压反应后血压恢复正常（1型；42%）或随后出现短暂血压下降（2型；7%）；血压升高后未随后下降（3型；3%）；血压先急剧升高，随后出现“经典”血管紧张素升压效应（4型；3%）；双相反应——降压反应后接着升压反应（5型；27%）；仅降压反应（6型；18%）。酚妥拉明和吲哚美辛可增强降压相，而阿托品和解痉药可抑制降压相。对血管紧张素II的反应似乎具有向量特征，胆碱能系统可减弱这种反应。
