Allen K D, Bartzokas C A, Graham R, Gibson M F, Gilbertson A A
Department of Medical Microbiology, Royal Liverpool Hospital.
J Hosp Infect. 1987 Sep;10(2):156-64. doi: 10.1016/0195-6701(87)90142-3.
During a 9-month period, patients, staff and environment were monitored in order to trace the source of endemic Pseudomonas aeruginosa on our intensive therapy unit (ITU). Of 81 patients studied, 14 (17%) acquired 15 different pyocin types while on the ITU. The most frequent site of colonization was the rectum (11 patients). Rectal strains subsequently appeared in urine (two patients), wound (one) and sputum (four) of six patients. Three episodes of cross-infection (wound (two), urine (one] occurred without development of rectal colonization. Strains isolated from the environment and staff were not implicated. While gastrointestinal carriage of P. aeruginosa may not be detected on admission to the ITU, excessive use of antibiotics may be responsible for apparent acquisition of the organism followed by endogenous transfer of the rectal strains to other sites of the body.
在9个月的时间里，对患者、医护人员和环境进行了监测，以追踪我们重症监护病房（ITU）内铜绿假单胞菌地方流行的源头。在研究的81名患者中，有14名（17%）在ITU期间感染了15种不同类型的绿脓菌素。最常见的定植部位是直肠（11名患者）。直肠菌株随后出现在6名患者的尿液（2名患者）、伤口（1名）和痰液（4名）中。发生了3起交叉感染事件（伤口感染2起、尿液感染1起），且没有出现直肠定植情况。从环境和医护人员中分离出的菌株与此无关。虽然在入住ITU时可能检测不到铜绿假单胞菌的胃肠道携带情况，但过度使用抗生素可能导致明显感染该病菌，随后直肠菌株内源性转移至身体其他部位。
