Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, The Netherlands.
Department of Medical Humanities, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht, Utrecht University, The Netherlands.
J Crit Care. 2018 Feb;43:148-155. doi: 10.1016/j.jcrc.2017.09.007. Epub 2017 Sep 6.
To assess the reliability of physicians' prognoses for intensive care unit (ICU) survivors with respect to long-term survival and health related quality of life (HRQoL).
We performed an observational cohort-study in a single mixed tertiary ICU in The Netherlands. ICU survivors with a length of stay >48h were included. At ICU discharge, one-year prognosis was estimated by physicians using the four-option Sabadell score to record their expectations. The outcome of interest was poor outcome, which was defined as dying within one-year follow-up, or surviving with an EuroQoL5D-3L index <0.4.
Among 1399 ICU survivors, 1068 (76%) subjects were expected to have a good outcome; 243 (18%) a poor long-term prognosis; 43 (3%) a poor short-term prognosis, and 45 (3%) to die in hospital (i.e. Sabadell score levels). Poor outcome was observed in 38%, 55%, 86%, and 100% of these groups respectively (concomitant c-index: 0.61). The expected prognosis did not match observed outcome in 365 (36%) patients. This was almost exclusively (99%) due to overoptimism. Physician experience did not affect results.
Prognoses estimated by physicians incorrectly predicted long-term survival and HRQoL in one-third of ICU survivors. Moreover, inaccurate prognoses were generally the result of overoptimistic expectations of outcome.
评估医生对 ICU 幸存者长期生存和健康相关生活质量(HRQoL)的预后的可靠性。
我们在荷兰的一家混合三级 ICU 进行了一项观察性队列研究。纳入 ICU 住院时间>48h 的幸存者。在 ICU 出院时,医生使用四选项萨瓦德尔评分来记录他们的预期,评估一年预后。主要结局为一年内死亡或生存时 EuroQoL5D-3L 指数<0.4。
在 1399 名 ICU 幸存者中,1068 名(76%)患者预计预后良好;243 名(18%)预后长期不良;43 名(3%)预后短期不良;45 名(3%)住院期间死亡(即萨瓦德尔评分水平)。分别有 38%、55%、86%和 100%的患者出现不良结局(同时一致性指数:0.61)。365 名(36%)患者的预期预后与实际结局不匹配。这几乎完全(99%)是由于过于乐观。医生经验并不影响结果。
医生估计的预后错误地预测了三分之一 ICU 幸存者的长期生存和 HRQoL。此外,不准确的预后通常是结果过于乐观的结果。