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分离性感觉障碍 - 回顾性病例系列及系统文献回顾。

Dissociative sensibility disorders - A retrospective case series and systematic literature review.

机构信息

University of Basel, University Children's Hospital Basel, Division of Neuropediatrics and Developmental Medicine, Switzerland.

University of Basel, University Children's Hospital Basel, Division of Neuropediatrics and Developmental Medicine, Switzerland.

出版信息

Eur J Paediatr Neurol. 2018 Jan;22(1):27-38. doi: 10.1016/j.ejpn.2017.08.005. Epub 2017 Sep 1.

Abstract

CONTEXT

Dissociative disorders present a huge challenge in clinical settings. In contrast to other dissociative symptoms, dissociative sensibility disorders are rarely focused on.

OBJECTIVE

To identify the clinical characteristics and outcomes of dissociative sensibility disorders in children and adolescents, and to review the use of diagnostic procedures.

DATA SOURCES

For the review, a literature search used Pubmed, Embase, Web of Science, and PubPsych (to 02/2015) and the reference lists of the studies identified.

STUDY SELECTION

Screening of titles and abstracts; full-text assessment by two reviewers.

DATA SELECTION

The original case series was identified by using the local data register.

DATA EXTRACTION

Two reviewers independently reviewed the data and, if they agreed on the relevance, extracted the data. In the original case series, data were extracted retrospectively from the records.

RESULTS

Sixteen studies and seven case reports were identified, including 931 cases with dissociative disorders. In 210 cases the patient suffered either from a single sensibility disorder or predominantly from sensibility disorders. We identified thirteen further cases in our cohort. In both groups there was female predominance; the mean age of manifestation was early adolescence. The timing of admissions was variable. In approximately 50% of cases a premorbid stressful life event could be identified. Over 75% of cases had a good prognosis with complete resolution.

LIMITATIONS

Retrospective character of our own data collection, partially missing differentiation between the subgroups of dissociative disorders in the reviewed studies.

CONCLUSIONS

There is no uniform procedure for diagnostic work-up. The overall short-term prognosis is good.

摘要

背景

分离性障碍在临床环境中带来巨大挑战。与其他分离性症状相反,分离性感觉障碍很少受到关注。

目的

确定儿童和青少年分离性感觉障碍的临床特征和结局,并回顾诊断程序的应用。

资料来源

为了进行综述,使用 Pubmed、Embase、Web of Science 和 PubPsych(截至 2015 年 2 月)检索文献,并查阅研究确定的参考文献列表。

研究选择

筛选标题和摘要;两名评审员对全文进行评估。

资料选择

使用当地数据登记册确定原始病例系列。

资料提取

两名评审员独立审查数据,如果他们认为相关,则提取数据。在原始病例系列中,数据从记录中回顾性提取。

结果

共确定了 16 项研究和 7 份病例报告,包括 931 例分离性障碍患者。210 例患者患有单一感觉障碍或主要为感觉障碍。我们在队列中还发现了另外 13 例病例。两组均以女性为主;发病的平均年龄为青春期早期。入院时间不定。大约 50%的病例可以识别出发病前的应激性生活事件。超过 75%的病例预后良好,完全缓解。

局限性

我们自己的资料收集具有回顾性,部分情况下综述中研究的分离性障碍亚组之间的区分缺失。

结论

目前没有统一的诊断程序。总体短期预后良好。

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